69726-38-1Relevant academic research and scientific papers
N - methylation of the sulfoxide of imine derivative (by machine translation)
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Paragraph 0029-0030, (2018/04/01)
A simple, clean and high-effective synthetic method of a novel N-methylated sulfoximine derivative is provided in the invention. The invention relates to the fields of pesticides, organic chemical engineering and fine chemical engineering. The method essentially is an organic synthesis reaction that a methyl free radical, which is generated from peroxides, and a sulfoximine compound are subjected to free radical coupling to form new C-N bonds. The method includes the step of carrying out a reaction to obtain the N-methylated sulfoximine derivative in a common organic solvent under a heating condition from the raw materials including diphenyl sulfoximine and a methylating reagent (peroxides) under the catalysis by copper. The method is 2-20 h in reaction time under a heating and stirring condition. The molar ratio of the raw materials is that the diphenyl sulfoximine to the methylating reagent is 1:0.5-3.0. The raw materials are reacted under the heating condition and then reaction products are subjected to simple after treatments to obtain the N-methylated sulfoximine derivative at a yield being 36-87%. The invention develops a series of N-methylating methods based on a free radical process to prepare a series of N-methylated sulfoximine derivatives. The method is simple in operation and after treatments, and is simple and practical in synthesis of these compounds.
Method for synthesizing diaromatic sulfoxide amine compound
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Paragraph 0042; 0043; 0044; 0045; 0057; 0058; 0066; 0067, (2017/08/25)
The invention relates to a method for synthesizing a diaromatic sulfoxide amine compound shown as the following formula (III) (see the formula in the specification). The method comprises the steps that in the nitrogen atmosphere and at room temperature, a
Copper-catalyzed N-methylation/ethylation of sulfoximines
Teng, Fan,Cheng, Jiang,Yu, Jin-Tao
supporting information, p. 9934 - 9937 (2015/10/12)
A protocol for the copper-catalyzed N-methylation of sulfoximines with di-tert-butyl peroxide (DTBP) was developed. This protocol has good functional group tolerance leading to N-methylated sulfoximines in moderate to good yields. Besides, N-ethylation of sulfoximines was achieved in the presence of bis(1,1-dimethylpropyl)peroxide as the ethylating agent under a standard procedure.
Preparation and Reactions of Sulfonimidoyl Fluorides
Johnson, Carl R.,Bis, Kostaki G.,Cantillo, Jose H.,Meanwell, Nicholas A.,Reinhard, Michael F. D.,et al.
, p. 1 - 3 (2007/10/02)
Sulfonimidoyl fluorides have been prepared for the first time by treatment of sulfonimidoyl chlorides with various sources of fluoride ion.Sulfonimidoyl chlorides are reduced to sulfinamides with alkyllithium reagents; however, the corresponding fluorides
