697299-82-4Relevant articles and documents
Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
-
Page/Page column 9, (2008/06/13)
Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Methods of treating hyperproliferative diseases in mammals are also disclosed.
Heterocyclic compounds
-
, (2008/06/13)
The present invention relates to substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. Specifically, the invention relates to quinazoline derivatives useful in treating disorders mediated by protein tyrosine kinase activity, in particular erbB-2 and/or EGFR activity.