6974-55-6

Basic information

• Product Name: 2-[(E)-2-(2-methoxyphenyl)ethenyl]quinoline
• Synonyms: 2-(2-(2-Methoxyphenyl)vinyl)quinoline; Methyl 2-(2-(2-quinolinyl)vinyl)phenyl ether
• CAS NO: 6974-55-6
• Molecular Formula: C₁₈H₁₅NO
• Molecular Weight: 261.3178
• Mol File: 6974-55-6.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 421.5°C at 760 mmHg
• Flash Point: 152.2°C
• Density: 1.166g/cm³
• Vapor Pressure: 6.36E-07mmHg at 25°C
• Refractive Index: 1.696
• CAS DataBase Reference: 2-[(E)-2-(2-methoxyphenyl)ethenyl]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(E)-2-(2-methoxyphenyl)ethenyl]quinoline(6974-55-6)
• EPA Substance Registry System: 2-[(E)-2-(2-methoxyphenyl)ethenyl]quinoline(6974-55-6)

Safety Data

• Hazardous Substances Data: 6974-55-6(Hazardous Substances Data)

Upstream product

• 62763-89-7 quinaldine hydrochloride 
• 135-02-4 ortho-anisaldehyde 
• 91-63-4 2-methylquinoline 
• 100200-70-2 N-(2-methoxybenzylidene)-p-toluenesulfonamide 
• 612-16-8 (2-methoxyphenyl)methanol 
• 6850-57-3 2-methoxybenzylamine 
• 1780-19-4 1,2,3,4-tetrahydro-2-methylquinoline 
• 77664-18-7 N-(2-methoxybenzyl)aniline 

Relevant articles and documents

Photophysics and excited-state proton transfer of 2′-hydroxy-2-trans- styrylquinoline

2-StQ-2OH possessing a proton donor group (hydroxy) and a proton acceptor group (quinoline) was synthesized in order to study the influence of structural effects on the excited-state proton transfer (ESPT) and tautomerization. The ESPT were observed for ground-state hydrogen-bonding complex between 2-StQ-2OH and 2,2,2-trifluoroethanol (TFE) or with triethylamine. In aqueous solution, ESPT can only be observed in α-cyclodextrin (α-CD) inclusion complex. The dielectric constant values of the α-CD cavities probed by 2-StQ-2OH and 2-StQ-2OMe are 8.5 and 6.3, respectively, because of the difference in size of the probe molecule inside the cavity.

Method for alkenylation of methyl heterocyclic compound

The invention discloses a method for alkenylation of methyl heterocyclic compound, which is a green method for synthesizing an alkenyl heterocyclic compound by carrying out alkenylation reaction on methyl under the condition that the methyl heterocyclic compound and alcohol do not need to participate in a transition metal catalyst. According to the method, alcohol which is cheap, easy to obtain, wide in source, stable and low in toxicity is used as an alkenylation reagent, no transition metal catalyst or ligand is needed, air can be directly used as a convenient, mild and efficient oxidizing agent under the action of common water-soluble inorganic base, and the method is suitable for industrial production. The alkenyl heterocyclic compound is directly synthesized by carrying out a Cenylation reaction with a methyl heterocyclic compound through processes such as oxidative condensation and the like. The method has the advantages of simple reaction conditions, no need of inert gas protection, low requirements on equipment, easiness in operation, water as a byproduct, easiness in removal of water-soluble inorganic base, no metal residue in the product, easiness in purification, suitability for heterocyclic systems such as quinoline, quinoxaline, pyridine, benzothiazole and the like, and wide application range, thereby having certain research significance and potential application prospect.

Preparation method of trans-disubstituted olefin

The invention relates to the technical field of organic chemical synthesis, and in particular, relates to a preparation method of trans-disubstituted olefin. According to the preparation method, primary alcohol and methyl azacycle are taken as raw materials, transition metal salt, nitric oxide and alkali are taken as catalysts, an organic solution is taken as a reaction medium, and reaction is carried out in an oxygen atmosphere. According to the preparation method, a reaction by-product is only water, the environment is not polluted, the required transition metal catalyst is cheap and easy toobtain, the reaction does not need high temperature, and the reaction cost and the requirements on reaction conditions can be reduced.

MnO2 mediated sequential oxidation/olefination of alkyl-substituted heteroarenes with alcohols

A practical and efficient ligand-free MnO2 mediated sequential oxidation and olefination has been developed for the facile synthesis of a broad range of unsaturated N-heteroazaarenes from simple alkyl-substituted heteroarenes and alcohols. The procedure tolerates a series of functional groups, such as methoxyl, chloro, bromo, iodo, vinyl, phenolic and hetero groups, providing the olefination products in moderate to good yields.The protocol could be conducted at mild conditions and used environmentally friendly air as the clear oxidant.