69746-39-0

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 100-19-6 (4-nitrophenyl)ethanone 
• 79-37-8 oxalyl dichloride 
• 74812-79-6 1-(4-nitrophenyl)-1-trimethylsilyloxyethylene 
• 66328-67-4 4-(4-nitrophenyl)-2,4-dioxobutanoic acid 

Downstream Products

• 100-19-6 (4-nitrophenyl)ethanone 
• 1193109-54-4 (2Z,5Z)-3-hydroxy-5-[3,3-dimethyl-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-ylidene]-1-(4-nitrophenyl)pent-2-ene-1,4-dione 

Relevant academic research and scientific papers

Furan-2,3-diones as masked dipoles: synthesis of isotetronic acids and mechanistic considerations

The formal dipolar behaviour of furan-2,3-diones is illustrated by their reaction with ethyl glyoxylate under Lewis basic activation uniquely, giving access to isotetronic derivatives. The Janus-type nature of the activated species, both nucleophilic and

Thermal addition reaction of aroylketene with 1-aryl-1- trimethylsilyloxyethylenes: Aromatic substituent effects of aroylketene and aryltrimethylsilyloxyethylene on their reactivity

The thermal addition reaction of various aroylketenes (C) generated by the thermolysis of 5-aryldioxofurans (A) to 1-aryl-1-trimethylsilyloxyethylenes gave 1,5-diarylpentane-1,3,5-triones (D) and 2,6-diaryl-4H-pyran-4-ones (E). The introduction of electron withdrawing substituents in the aroylketene and of electron donating substituents facilitated the addition reaction. The observed substituent effects and the reaction mechanism are interpreted in terms of molecular orbital analyses.

Reactions of 5-aryl-furan-2,3-diones with acylmethylenetriphenylphosphoranes: Synthesis and biological activity of 3(2H)-furanone derivatives

The Wittig reaction of 5-aryl-furan-2,3-diones 1 with acylmethylenetriphenylphosphoranes 2 conducted by heating under reflux in benzene solutions, proceeded regiospecifically to afford 2-acylmethylene-5-aryl-3(2H)-furanones 5 in good yields. When the star