69816-38-2

Usage

Uses

Used in Organic Synthesis:
2-Amino-5-(trifluoromethyl)pyrazine serves as a building block in organic synthesis, contributing to the creation of a wide range of chemical compounds. Its unique structure allows for versatile reactions and the formation of diverse products.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-Amino-5-(trifluoromethyl)pyrazine is utilized as a key component in the synthesis of pharmaceuticals. Its presence in these compounds can influence their biological activity and therapeutic potential.
Used in Flavor and Fragrance Industry:
2-Amino-5-(trifluoromethyl)pyrazine is employed as a flavor and fragrance ingredient, adding unique scents and tastes to food and cosmetic products. Its ability to impart distinct sensory characteristics makes it valuable in these applications.
Used in Agrochemicals:
2-Amino-5-(trifluoromethyl)pyrazine also finds use in the agrochemical industry, where it is incorporated into the synthesis of various agrochemical products. Its role in these compounds can enhance their effectiveness in agricultural applications.
Safety and Storage:
As a white to light brown crystalline solid with a melting point of 106-108°C, 2-Amino-5-(trifluoromethyl)pyrazine requires careful handling to prevent skin irritation. It should be stored in a cool, dry place, away from heat and sources of ignition to ensure safety and maintain its stability.

Upstream product

• 431-67-4 1,1-dibromo-3,3,3-trifluoroacetone 
• 1672-50-0 4,5-diamino-6-hydroxypyrimidine 
• 799557-87-2 2-chloro-5-(trifluoromethyl)-pyrazine 

Downstream Products

• 1196152-38-1 2-bromo-5-(trifluoromethyl)-pyrazine 
• 1260667-12-6 2-amino-3-chloro-5-(trifluoromethyl)pyrazine 
• 1372197-49-3 6-(trifluoromethyl)imidazo[1,2-a]pyrazine-2-carboxylic acid 
• 1360055-12-4 6-tert-butyl-8-fluoro-2-{2-hydroxymethyl-3-[1-methyl-6-oxo-5-(5-trifluoromethyl-pyrazin-2-ylamino)-1,6-dihydro-pyridazin-3-yl]-phenyl}-2H-phthalazin-1-one 
• 1160608-05-8 [2-(2,6-Dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(5-trifluoromethyl-pyrazin-2-yl)-amine 
• 134510-03-5 5-(trifluoromethyl)-pyrazin-2(1H)-one 

Relevant academic research and scientific papers

CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS

This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-y which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

HETERCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE

Described herein are heterocyclic compounds, compositions, and methods for their use for treatment of disease.

HETEROCYCLIC COMPOUNDS AS PI3K-y INHIBITORS

This application relates to compounds of Formula (I): or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER

2-hydroxy-benzoic anilide compounds and derivatives, compositions thereof, and methods for treating metabolic diseases and cancer through uncoupling mitochondria.

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.

COMPOUNDS USEFUL FOR INHIBITING CHK1

Aryl- and heteroaryl-substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in tre

Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas

Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas, active as insecticides, and methods for their use as insecticides.