799557-87-2Relevant academic research and scientific papers
Method for synthesizing 2-chloro-5-(trifluoromethyl)pyrazine
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Paragraph 0030; 0032; 0033; 0042; 0045, (2018/05/03)
The invention provides a method for synthesizing 2-chloro-5-(trifluoromethyl)pyrazine by using 5-chloro-pyrazine-2-carboxylic acid, anhydrous hydrogen fluoride and sulfur tetrafluoride. The method forsynthesizing 2-chloro-5-(trifluoromethyl)pyrazine has the advantages of simple technology, easily available raw materials, and high yield.
SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS
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Page/Page column 26, (2010/02/10)
The present invention relates to novel piperidine ether derivatives having affinity for the histamine H3 receptor, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
PIPERAZINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISEASES
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Page 27, (2008/06/13)
The present invention relates to novel piperidine carbonyl piperazine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
