69840-49-9 Usage
Chemical class
Imidazole
Structural features
Phenylbenzyl group attached to the imidazole ring
Two carboxylic acid groups located at the 4 and 5 positions
Potential applications
Pharmaceutical research
Drug development
Biological activities
Unknown, but may have potential due to structural features
Synthesis
Can be used as a building block for the synthesis of other chemical compounds
Further research
Required to fully understand its potential uses and properties
Safety and toxicity
Not mentioned in the material provided, but should be considered in further research and testing
Stability
Not mentioned in the material provided, but should be considered in further research and testing
Solubility
Not mentioned in the material provided, but should be considered in further research and testing
Reactivity
Not mentioned in the material provided, but should be considered in further research and testing
Check Digit Verification of cas no
The CAS Registry Mumber 69840-49-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,8,4 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 69840-49:
(7*6)+(6*9)+(5*8)+(4*4)+(3*0)+(2*4)+(1*9)=169
169 % 10 = 9
So 69840-49-9 is a valid CAS Registry Number.
69840-49-9Relevant articles and documents
Chiral azole derivatives. 2. Synthesis of enantiomerically pure 1-alkylimidazoles
Corelli,Summa,Brogi,Monteagudo,Botta
, p. 2008 - 2015 (2007/10/02)
4,5-Dicyanoimidazole has been reacted with racemic and enantiopure alcohols 7 (entries 1-7) under Mitsunobu conditions to give 1-alkyl-4,5-dicyanoimidazole derivatives 8, which in turn have been transformed by hydrolysis and decarboxylation into 1-alkylimidazoles 10 in good overall yield and high enantiomeric excess. In contrast, when applied to benzyl and benzhydryl alcohols (entries 8-15), this sequence afforded the final compounds in good overall yield, but as racemic mixtures. The 1-(1-phenylalkyl)imidazole derivative (S)-(+)-24 was, however, prepared in enantiopure form starting from the corresponding (S)-(-)-α-methylbenzylamine (21) using the Marckwald procedure, which entailed the alkylation of 21 with bromoacetaldehyde dimethyl acetal, followed by the construction of the imidazole ring through reaction with potassium thiocyanate and final Ra-Ni desulfuration. Following the same procedure, (S)-(+)-10c was also synthesized, proving the stereochemical outcome of the Mitsunobu reaction.
