7189-67-5

Basic information

• Product Name: 1-BENZHYDRYL-1H-IMIDAZOLE
• Synonyms: 1-BENZHYDRYL-1H-IMIDAZOLE
• CAS NO: 7189-67-5
• Molecular Formula: C₁₆H₁₄N₂
• Molecular Weight: 234.2958
• Mol File: 7189-67-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 383.4°Cat760mmHg
• Flash Point: 185.7°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 9.71E-06mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: 1-BENZHYDRYL-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZHYDRYL-1H-IMIDAZOLE(7189-67-5)
• EPA Substance Registry System: 1-BENZHYDRYL-1H-IMIDAZOLE(7189-67-5)

Safety Data

• Hazardous Substances Data: 7189-67-5(Hazardous Substances Data)

Usage

General Description

1-BENZHYDRYL-1H-IMIDAZOLE is an organic compound with the molecular formula C15H16N2. It is a heterocyclic compound containing an imidazole ring and a benzhydryl group. 1-BENZHYDRYL-1H-IMIDAZOLE is used in organic synthesis as a building block for heterocyclic compounds and pharmaceuticals. It has been studied for its potential as an anti-inflammatory and antifungal agent.1-BENZHYDRYL-1H-IMIDAZOLE has also been investigated for its role in metal ion binding and metalloenzyme inhibition. Overall, this compound has a variety of potential applications in medicinal chemistry and drug development.

InChI:InChI=1/C16H14N2/c1-3-7-14(8-4-1)16(18-12-11-17-13-18)15-9-5-2-6-10-15/h1-13,16H

Upstream product

• 288-32-4 1H-imidazole 
• 90-99-3 diphenylchloromethane 
• 69840-49-9 1-(α-Phenylbenzyl)imidazole-4,5-dicarboxylic acid 
• 50-00-0 formaldehyd 
• 131543-46-9 Glyoxal 
• 91-00-9 Benzhydrylamine 
• 119-61-9 benzophenone 
• 908093-98-1 diazodiphenylmethane 
• 776-74-9 Bromodiphenylmethane 
• 69840-48-8 1-(α-Phenylbenzyl)imidazole-4,5-dicarbonitrile 
• 91-01-0 1,1-Diphenylmethanol 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 496067-91-5 3-benzhydryl-1-[2-(2-tert-butyl-4,5-dihydro-oxazol-4-yl)-ethyl]-3H-imidazol-1-ium; iodide 
• 496067-61-9 1-(((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-diphenylmethylimidazolium iodide 
• 776-74-9 Bromodiphenylmethane 
• 169382-84-7 1-benzhydryl-3,5-bis(chloromethyl)-1H-1,2,4-triazole 
• 169382-85-8 1-Benzhydryl-3,5-bis-imidazol-1-ylmethyl-1H-[1,2,4]triazole 
• 431947-50-1 1-benzhydryl-3,5-bis-(4,5-dimethyl-imidazol-1-ylmethyl)-1H-[1,2,4]triazole 
• 452972-99-5 1-benzhydryl-3,5-bis(hydroxymethyl)-1H-1,2,4-triazole 
• 1332836-23-3 1-benzhydryl-3-(butyl)imidazol-3-ium bromide 
• 1332836-25-5 1-benzhydryl-3-(octyl)imidazol-3-ium bromide 
• 1332836-26-6 1-benzhydryl-3-(decyl)imidazol-3-ium bromide 
• 1332836-28-8 1-benzhydryl-3-(tetradecyl)imidazol-3-ium bromide 
• 1332836-31-3 1-benzhydryl-3-(2-benzyloxyethyl)imidazol-3-ium bromide 
• 1332836-30-2 1-benzhydryl-3-(2-phenylethyl)imidazol-3-ium bromide 
• 286014-46-8 1-diphenylmethyl-3-methylimidazolium iodide 

Relevant articles and documents

Polynuclear Ag(I)-N-heterocyclic carbene complexes: synthesis, electrochemical and in vitro anticancer study against human breast cancer and colon cancer

Four new bis-imidazolium salts 3–6 and their di- and polynuclear silver(I)–N-heterocyclic carbene (Ag(I)–NHC) complexes 7–10 were synthesized and characterized by using various analytical techniques. Single-crystal studies of 8 revealed a dinuclear struct

Stable group 8 metal porphyrin mono- And bis(dialkylcarbene) complexes: Synthesis, characterization, and catalytic activity

Alkyl-substituted carbene (CHR or CR2, R = alkyl) complexes have been extensively studied for alkylcarbene (CHR) ligands coordinated with high-valent early transition metal ions (a.k.a. Schrock carbenes or alkylidenes), yet dialkylcarbene (CR2) complexes remain less developed with bis(dialkylcarbene) species being little (if at all) explored. Herein, several group 8 metal porphyrin dialkylcarbene complexes, including Fe- and Ru-mono(dialkylcarbene) complexes [M(Por)(Ad)] (1a,b, M = Fe, Por = porphyrinato dianion, Ad = 2-adamantylidene; 2a,b, M = Ru) and Os-bis(dialkylcarbene) complexes [Os(Por)(Ad)2] (3a-c), are synthesized and crystallographically characterized. Detailed investigations into their electronic structures reveal that these complexes are formally low-valent M(ii)-carbene in nature. These complexes display remarkable thermal stability and chemical inertness, which are rationalized by a synergistic effect of strong metal-carbene covalency, hyperconjugation, and a rigid diamondoid carbene skeleton. Various spectroscopic techniques and DFT calculations suggest that the dialkylcarbene Ad ligand is unique compared to other common carbene ligands as it acts as both a potent σ-donor and π-acceptor; its unique electronic and structural features, together with the steric effect of the porphyrin macrocycle, make its Fe porphyrin complex 1a an active and robust catalyst for intermolecular diarylcarbene transfer reactions including cyclopropanation (up to 90% yield) and X-H (X = S, N, O, C) insertion (up to 99% yield) reactions.

LuxR dependent quorum sensing inhibition by N,N′-disubstituted imidazolium salts

Thirty N,N′-disubstituted imidazolium salts have been synthesized and evaluated as LuxR antagonists. Substitution on one of the imidazolium nitrogen atoms includes benzhydryl, fluorenyl or cyclopentyl substituent, and alkyl chains of various lengths on th