69871-80-3Relevant academic research and scientific papers
Probing enzyme stereospecificity. Evaluation of β-alkoxy-α-amino acids with two stereocenters as inhibitors of serine proteases
Lee,Jones
, p. 7331 - 7346 (1995)
L-N-Acetyl-O-(arylalkyl)-serines incorporating two stereocenters were prepared via ring-opening reactions of an aziridine precursor, derived from L-serine, with each of R and S 1-phenyl- and 2-methoxy-3-phenylethanol. These were then evaluated as inhibito
[Asn2 ]-thymosin α1 and analogs thereof
-
, (2008/06/13)
Thymosin α1, was chemically synthesized by the fragment condensation of the protected amino terminal tetradecapeptide with the protected carboxyl terminal tetradecapeptide. Similarly prepared was the analog [Asn2 ]-thymosin α1 utilizing the appropriately modified protected amino terminal tetradecapeptide. Both products are active as agents which affect regulation, differentiation and function of thymus dependent lymphocytes (T cells).
