Probing enzyme stereospecificity. Evaluation of β-alkoxy-α-amino acids with two stereocenters as inhibitors of serine proteases

DOI: 10.1016/0040-4020(95)00382-I

Source and publish data:

Tetrahedron p. 7331 - 7346 (1995)

Update date:2022-08-05

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Authors:

Lee Lee

Jones Jones

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Article abstract of DOI:10.1016/0040-4020(95)00382-I

L-N-Acetyl-O-(arylalkyl)-serines incorporating two stereocenters were prepared via ring-opening reactions of an aziridine precursor, derived from L-serine, with each of R and S 1-phenyl- and 2-methoxy-3-phenylethanol. These were then evaluated as inhibito

Full text of DOI:10.1016/0040-4020(95)00382-I

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