Probing enzyme stereospecificity. Evaluation of β-alkoxy-α-amino acids with two stereocenters as inhibitors of serine proteases

DOI: 10.1016/0040-4020(95)00382-I

Source and publish data:

Tetrahedron p. 7331 - 7346 (1995)

Update date:2022-08-05

Topics:

Authors:

Lee Lee

Jones Jones

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00382-I

L-N-Acetyl-O-(arylalkyl)-serines incorporating two stereocenters were prepared via ring-opening reactions of an aziridine precursor, derived from L-serine, with each of R and S 1-phenyl- and 2-methoxy-3-phenylethanol. These were then evaluated as inhibito

Full text of DOI:10.1016/0040-4020(95)00382-I

Products guided by the article

Product name:N-acetyl-O-benzyl-L-serine benzyl ester

Cas No:69871-80-3

R&D Labs maybe for 69871-80-3

Shanghai Yurui Biotechnology(Anyang) Pharmaceutical Co., Ltd

Contact:+86-0372-3662335 +86-0372-3661988

Address:hanling industrial park anyang
Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Hunan Dinuo Pharmaceutical Co.,Ltd.

Contact:86-731-88280100*8561

Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
xuri chemicals co., ltd

Contact:86-516-66656369

Address:The west road of Huaihai, Xuzhou, China

Relevant to this article

Doi:10.1016/0040-4020(78)88383-5
(1978)
Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure–activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study

Doi:10.1016/j.bioorg.2021.104795
(2021)
Inhibition studies with rationally designed inhibitors of the human low molecular weight protein tyrosine phosphatase

Doi:10.1016/j.bmc.2004.01.042
(2004)
Chirality Exchange from sp³ Central Chirality to Axial Chirality: Benzannulation of Optically Active Diaryl-2,2-dichlorocyclopropylmethanols to Axially Chiral α -Arylnaphthalenes

Doi:10.1021/ja0319442
(2004)
Saegusa Oxidation of Enol Ethers at Extremely Low Pd-Catalyst Loadings under Ligand-free and Aqueous Conditions: Insight into the Pd(II)/Cu(II)-Catalyst System

Doi:10.1021/acs.joc.0c02987
(2021)
Improved Access to Imidazole-phosphonic Acids: Synthesis of D-manno-Tetrahydroimidazopyridine-2-phosphonates)

Doi:10.1002/hlca.200490067
(2004)

Article Doi