698985-45-4

Usage

Benzene ring

Aromatic structure
The backbone of the compound, consisting of six carbon atoms connected in a hexagonal ring with alternating single and double bonds.

Nitro group

-NO2
A functional group consisting of an oxygen-nitrogen-oxygen atom chain, attached to the benzene ring, contributing to the compound's reactivity and properties.

Hydroxyl groups

-OH (two present)
A functional group consisting of an oxygen atom bonded to a hydrogen atom, present at two positions on the benzene ring, influencing the compound's polarity and solubility.

Fluorine atom

-F
A halogen atom attached to the benzene ring at the 5th position, affecting the compound's reactivity, electronegativity, and physical properties.

Pharmaceutical applications

Production of various pharmaceuticals
Utilized as an intermediate or building block in the synthesis of different drugs, contributing to the development of new medications.

Organic synthesis

Use in chemical reactions
Employed in various chemical reactions to form new compounds, showcasing its versatility in organic chemistry.

Fluorescent probe

Detection of biological substances
Possesses the potential to be used as a fluorescent probe for identifying and monitoring specific biological materials, offering valuable insights in research and diagnostics.

Hazardous chemical

Potentially harmful effects
Requires careful handling and proper safety measures due to its potential to cause harm to human health and the environment if mismanaged.

Upstream product

• 394-32-1 1-(5-fluoro-2-hydroxyphenyl)ethan-1-one 
• 70978-39-1 5'-fluoro-2'-hydroxy-3'-nitroacetophenone 

Relevant academic research and scientific papers

SUBSTITUTED IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TrkA) INHIBITORS

The present application relates to a series of substituted imidazo[1,2-a]pyridine compounds of formula (I), pharmaceutically acceptable salts, pharmaceutically acceptable solvates or stereoisomers thereof, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.

SUBSTITUTED PYRAZOLO[1,5-A] PYRIDINE AS TROPOMYOSIN RECEPTOR KINASE (TRK) INHIBITORS

The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.

SUBSTITUTED PYRAZOLO[1,5-A] PYRIDINE AS TROPOMYOSIN RECEPTOR KINASE (TRK) INHIBITORS

The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors., method of making and pharmaceutical compositions comprising such compounds.

Synthesis of 7-substituted-(2,3-dihydro-1,4-benzodioxin-5-yl)-piperazine

A simple and versatile method for the synthesis of 7-substituted (2,3-dihydro-1,4-benzodioxin-5-yl)-piperazines starting from easy available class of derivatives has been developed. Copyright Taylor & Francis Group, LLC.