699009-76-2

Upstream product

• 433735-03-6 (6S)-1-benzyl-5-ethoxy-3,6-dihydro-6-isopropylpyrazine-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 699009-78-4 (3R,6S)-1-Benzyl-3-(2-chloromethyl-allyl)-5-ethoxy-6-isopropyl-3-methyl-3,6-dihydro-1H-pyrazin-2-one 
• 699009-86-4 (3S,6R)-4-benzyl-6-methyl-8-methylene-2,5-diketo-3-isopropyl-1,4-diazabicyclo[4.3.0]nonane 
• 699009-80-8 (3R,6S)-1-Benzyl-3-[2-((2R,5S)-4-benzyl-6-ethoxy-5-isopropyl-3-oxo-2,3,4,5-tetrahydro-pyrazin-2-ylmethyl)-allyl]-5-ethoxy-6-isopropyl-3-methyl-3,6-dihydro-1H-pyrazin-2-one 
• 834883-04-4 ortho-bis-[(3R,6S)-3,6-dihydro-5-ethoxy-6-isopropyl-3-methyl-pyrazin-2-one-3-methylene]benzene 
• 834883-03-3 ortho-bis-[(3R,6S)-1-benzyl-3,6-dihydro-5-ethoxy-6-isopropyl-3-methyl-pyrazin-2-one-3-methylene]benzene 

Relevant academic research and scientific papers

Stereoselective synthesis of pseudotripeptides incorporating uncommon bis-α-aminoacid derivatives and X-ray analysis. Part 3

Stereoselective synthesis of pseudotripeptides 4, 5, 6, 8, 9, 13 and 14, incorporating an uncommon bis(α-aminoacid) derivative, has been accomplished starting from the L-valine derived chiral synthon 1. The configuration of the introduced stereogenic cent

Enantioselective synthesis of pseudotripeptides incorporating a γ-methylene derivative of 2,6-diaminopimelic acid: Part 6

An efficient enantioselective synthesis of pseudotripeptides 5, 8a-d and 13a and b incorporating a 2,6-diamino-4-methylene-1,7-heptandioic acid residue, has been accomplished starting from the glycine derived chiral synthon 1 (from L-valine). The absolute configuration of the new stereocentres was assigned on the basis of 1H NMR spectra. The geometry of derivative 4 was deduced on the basis of 1H NMR parameters (δNH value, temperature coefficient, δNH change upon addition of DMSO or CD3OD, NOE studies) and IR spectra.