699009-76-2

Upstream product

• 433735-03-6 (6S)-1-benzyl-5-ethoxy-3,6-dihydro-6-isopropylpyrazine-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 699009-78-4 (3R,6S)-1-Benzyl-3-(2-chloromethyl-allyl)-5-ethoxy-6-isopropyl-3-methyl-3,6-dihydro-1H-pyrazin-2-one 
• 834883-03-3 ortho-bis-[(3R,6S)-1-benzyl-3,6-dihydro-5-ethoxy-6-isopropyl-3-methyl-pyrazin-2-one-3-methylene]benzene 
• 699009-80-8 (3R,6S)-1-Benzyl-3-[2-((2R,5S)-4-benzyl-6-ethoxy-5-isopropyl-3-oxo-2,3,4,5-tetrahydro-pyrazin-2-ylmethyl)-allyl]-5-ethoxy-6-isopropyl-3-methyl-3,6-dihydro-1H-pyrazin-2-one 
• 834883-04-4 ortho-bis-[(3R,6S)-3,6-dihydro-5-ethoxy-6-isopropyl-3-methyl-pyrazin-2-one-3-methylene]benzene 
• 699009-86-4 (3S,6R)-4-benzyl-6-methyl-8-methylene-2,5-diketo-3-isopropyl-1,4-diazabicyclo[4.3.0]nonane 

Relevant academic research and scientific papers

Enantioselective synthesis of pseudotripeptides incorporating a γ-methylene derivative of 2,6-diaminopimelic acid: Part 6

An efficient enantioselective synthesis of pseudotripeptides 5, 8a-d and 13a and b incorporating a 2,6-diamino-4-methylene-1,7-heptandioic acid residue, has been accomplished starting from the glycine derived chiral synthon 1 (from L-valine). The absolute configuration of the new stereocentres was assigned on the basis of 1H NMR spectra. The geometry of derivative 4 was deduced on the basis of 1H NMR parameters (δNH value, temperature coefficient, δNH change upon addition of DMSO or CD3OD, NOE studies) and IR spectra.

Stereoselective synthesis of pseudotripeptides incorporating uncommon bis-α-aminoacid derivatives and X-ray analysis. Part 3

Stereoselective synthesis of pseudotripeptides 4, 5, 6, 8, 9, 13 and 14, incorporating an uncommon bis(α-aminoacid) derivative, has been accomplished starting from the L-valine derived chiral synthon 1. The configuration of the introduced stereogenic cent