69902-43-8Relevant academic research and scientific papers
The Reactions of α-Monosubstituted Primary Amines with 1,4-Dimethyl-6-hydroxycarbazole and 9-Hydroxyellipticine under Oxidative Conditions: Formation of a Novel Series of Annulated Oxazoles
Sundaramoorthi, Rajeswari,Kansal, Vinod K.,Das, Bhupesh C.,Potier, Pierre
, p. 371 - 372 (1986)
The oxidative nucleophilic addition reactions of α-monosubstituted primary amines (RCH2NH2) with a 5-hydroxyindole-containing molecular framework such as 1,4-dimethyl-6-hydroxycarbazole and 9-hydroxyellipticine in the presence of manganese dioxide led to
Identification of Lead Compounds as Inhibitors of STAT3: Design, Synthesis and Bioactivity
Botta, Antonio,Sirignano, Esther,Popolo, Ada,Saturnino, Carmela,Terracciano, Stefania,Foglia, Antonio,Sinicropi, Maria Stefania,Longo, Pasquale,Di Micco, Simone
, p. 689 - 697 (2015/10/28)
STAT3 belongs to the signal transducers and activators of transcription (STAT) family. It has been demonstrated that STAT3 is constitutively activated in many tumors, playing a role in carcinogenesis and tumor progression. For this reason, it has being co
New trimethoxybenzamides and trimethoxyphenylureas derived from dimethylcarbazole as cytotoxic agents. Part i
Panno, Antonella,Sinicropi, Maria Stefania,Caruso, Anna,El-Kashef, Hussein,Lancelot, Jean-Charles,Aubert, Geneviève,Lesnard, Aurélien,Cresteil, Thierry,Rault, Sylvain
, p. E294-E302 (2014/11/08)
A convenient synthesis of novel functionalized 1,4-dimethylcarbazole derivatives containing 3,4,5-trimethoxybenzamido-ureido or N-(3,4,5- trimethoxyphenyl)ureido group starting from their corresponding indole derivatives is reported. Three derivatives pre
Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: Part i
Caruso, Anna,Chimento, Adele,El-Kashef, Hussein,Lancelot, Jean-Charles,Panno, Antonella,Pezzi, Vincenzo,Saturnino, Carmela,Sinicropi, Maria Stefania,Sirianni, Rosa,Rault, Sylvain
body text, p. 609 - 613 (2012/09/22)
Several 9H-carbazole derivatives are used for various pharmacological applications. Many of these compounds demonstrated cytotoxic and anticancer activities. In this work, we have investigated the cytotoxic activity of some substituted carbazoles against
Novel and efficient synthesis of 5,8-dimethyl-9H-carbazol-3-ol via a hydroxydeboronation reaction
Caruso, Anna,Voisin-Chiret, Anne Sophie,Lancelot, Jean-Charles,Sinicropi, Maria Stefania,Garofalo, Antonio,Rault, Sylvain
, p. 2203 - 2210 (2008/09/17)
N-Protected carbazol-3-yl-boronic acid derivatives have been efficiently hydroxydeboronated under mild conditions by employing hydrogen peroxide. The method allows to easily obtain 3-hydroxycarbazoles as precursors of new analogs of the anticancer agent 9-hydroxyellipticine.
2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine
-
, (2008/06/13)
Derivatives of 9-hydroxy ellipticine, preparation thereof, and use thereof for the treatment of leukemias and solid tumors.
