699020-36-5Relevant academic research and scientific papers
Asymmetric synthesis of N,O-diprotected (2S,3S)-N-methyl-δ- hydroxyisoleucine, noncoded amino acid of halipeptin A
Izzo, Irene,Avallone, Elvira,Della Corte, Luca,Maulucci, Nakia,De Riccardis, Francesco
, p. 1181 - 1186 (2004)
The first enantioselective synthesis of N,O-diprotected (2S,3S)-N-methyl-δ-hydroxyisoleucine 4, starting from readily available (tert-butyldimethylsilyl)-2-butyn-1-ol 5, is described. The key steps of this stereochemical flexible synthetic route involve a
