69912-09-0Relevant academic research and scientific papers
Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists.
Micheli, Fabrizio,Fabio, Romano Di,Cavanni, Paolo,Rimland, Joseph M,Capelli, Anna Maria,Chiamulera, Cristiano,Corsi, Mauro,Corti, Corrado,Donati, Daniele,Feriani, Aldo,Ferraguti, Francesco,Maffeis, Micaela,Missio, Andrea,Ratti, Emiliangelo,Paio, Alfredo,Pachera, Roberta,Quartaroli, Mauro,Reggiani, Angelo,Sabbatini, Fabio Maria,Trist, David G,Ugolini, Annarosa,Vitulli, Giovanni
, p. 171 - 183 (2003)
Metabotropic glutamate receptors (mGluRs) are an unusual family of G-protein coupled receptor (GPCR), and are characterised by a large extracellular N-terminal domain that contains the glutamate binding site. We have identified a new class of non-competit
Asymmetric synthesis of mono- and dinuclear bis(dipyrrinato) complexes
Ali, Adeeb Al-Sheikh,Benson, Ronald E.,Blumentritt, Sascha,Cameron, T. Stanley,Linden, Anthony,Wolstenholme, David,Thompson, Alison
, p. 4947 - 4952 (2008/02/05)
(Chemical Equation Presented) The diastereoselective syntheses of Zn(II) bis(dipyrrinato) helicates is reported, involving ligands templated by the incorporation of homochiral binol within the linker joining the two dipyrrinato units. The most diastereose
Efficient method for the synthesis of bisaminoethanethiols and their pyrrole conjugates
Li, Guolin,Ma, Qinggago,Ma, Bing,Grossman, Zachary D.,Pandey, Ravindra K.
, p. 2849 - 2854 (2007/10/03)
By following the protection and deprotection approach, an efficient method for the preparation of bisaminoethanethiol ligands (N2S2) is discussed. In our attempts to synthesize certain nonpeptide analogs of neurotensin, moldel studies were performed by using these ligands for preparing the corresponding pyrrole based conjugates. This methodology provides an alternate approach for developing various target specific agents that cross the blood brain barrier.
TOTAL SYNTHESES OF MONO-, DI-, AND TRI-PROPIONIC PORPHYRINS FOR STUDIES OF THE MECHANISM OF HEME-APOPROTEIN RECONSTITUTION
Pandey, Ravindra K.,Rezzano, Irene N.,Smith, Kevin M.
, p. 2171 - 2192 (2007/10/02)
Total syntheses of eight new porphyrins bearing either one (14), two (8, 15, 28, 29, 51) or three (42, 43) propionic side chains in variously permutated positions around the porphyrin periphery are described.Compound (8) was prepared using the MacDonald (
