69940-73-4Relevant academic research and scientific papers
A mild and selective reduction of β-lactams: Rh-catalyzed hydrosilylation towards important pharmacological building blocks
Bornschein, Christoph,Lennox, Alastair J. J.,Werkmeister, Svenja,Junge, Kathrin,Beller, Matthias
, p. 1915 - 1919 (2015)
Four-membered N-heterocyclic compounds exhibit a broad range of pharmacological activities. Herein, we report a useful rhodium-catalyzed protocol for the activation of phenylsilane to reduce tertiary β-lactams. Reaction with the tertiary amides was select
Reduction of N-Substituted Azetidin-2-ones to Azetidines
Jackson, Mervyn B.,Mander, Lewis N.,Spotswood, Thomas M.
, p. 779 - 788 (2007/10/02)
Reduction of N-substituted azetidin-2-ones to N-substituted azetidines was accomplished rapidly and in good yield with diborane in tetrahydrofuran and with alane in ether.The stereochemistry of the ring substituents was retained under the reaction conditi
