69945-42-2

Basic information

• Product Name: 2,6-Pyridinedicarbothioicacid(9CI)
• Synonyms: 2,6-Pyridinedicarbothioicacid(9CI);Cpd-8207;Pyrimidine-2,6-bis(thiocarboxylate);Pyrimidine-2,6-bis(thiocarboxylic acid)
• CAS NO: 69945-42-2
• Molecular Formula: C₇H₅NO₂S₂
• Molecular Weight: 199.25
• Product Categories: PYRIDINE
• Mol File: 69945-42-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Pyridinedicarbothioicacid(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Pyridinedicarbothioicacid(9CI)(69945-42-2)
• EPA Substance Registry System: 2,6-Pyridinedicarbothioicacid(9CI)(69945-42-2)

Safety Data

• Hazardous Substances Data: 69945-42-2(Hazardous Substances Data)

Usage

General Description

2,6-Pyridinedicarbothioicacid(9CI) is a chemical compound with the molecular formula C7H4N2O2S2. It is a sulfur-containing heterocyclic compound with a pyridine ring and two carbothioic acid groups. 2,6-Pyridinedicarbothioicacid(9CI) is commonly used as a chelating agent in metal complexation studies and as a building block in organic synthesis. It has the potential to form stable complexes with various metal ions, making it useful in the fields of chemistry and biochemistry. Additionally, 2,6-Pyridinedicarbothioicacid(9CI) has been investigated for its potential antioxidant and anti-inflammatory properties, showing promise for use in pharmaceutical and medical applications.

Upstream product

• 3739-94-4 2,6-Pyridinedicarbonyl dichloride 
• 88418-26-2 pyridinium pyridinium-2,6-dicarbothioate 

Downstream Products

• 109749-42-0 essigsaeure-pyridin-2,6-dicarbonsaeure-bis-thioanhydrid 
• 1428772-35-3 C₁₇H₁₃NO₃STi 
• 1161863-05-3 [Ni₃(DMF)3(pyridine-2,6-dithiocarboxylate)3]*DMF 
• 155641-27-3 pyridine-2,6-bis(methylthiocarboxylato)palladium iodide 
• 1161863-03-1 [Ni₂(pyridine-2,6-dithiocarboxylate)2] 
• 155641-21-7 (Pd(C₅H₃N(C(O)S)2))2 
• 69945-43-3 Pyridin-2,6-di(monothiocarbonsaeure)-di-S-methyl ester 

Relevant articles and documents

Pyridine-2,6-dithiocarboxylic acid and its metal complexes: New inhibitors of New Delhi metallo β-Lactamase-1

Carbapenem-resistant Enterobacteriaceae continue to threaten human health worldwide with few effective treatment options. New Delhi metallo-β-lactamase (NDM) enzymes are a contributing element that drive resistance to many β-lactam- and carbapenem-based antimicrobials. Many NDM inhibitors are known, yet none are clinically viable. In this study, we present and characterize a new class of NDM-1 inhibitors based on a pyridine-2,6-dithiocarboxylic acid metal complex scaffold. These complexes display varied and unique activity profiles against NDM-1 in kinetic assays and serve to increase the effectiveness of meropenem, an established antibacterial, in assays using clinical Enterobacteriaceae isolates.

Solid-to-solid oxidation of a vanadium(IV) to a vanadium(V) compound: Chemisty of a sulfur-containing siderophore

Visible light facilitates a solid-to-solid photochemical aerobic oxidation of a hunter-green microcrystalline oxidovanadium(IV) compound (1) to form a black powder of cis-dioxidovanadium(V) (2) at ambient temperature. The siderophore ligand pyridine-2,6-bis(thiocarboxylic acid), H2L, is secreted by a microorganism from the Pseudomonas genus. This irreversible transformation of a metal monooxo to a metal dioxo complex in the solid state in the absence of solvent is unprecedented. It serves as a proof-of-concept reaction for green chemistry occurring in solid matrixes.