69949-67-3Relevant academic research and scientific papers
NOVEL SUBSTITUTED PYRIDO-PIPERAZINONE DERIVATIVES AS GAMMA SECRETASE MODULATORS
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Paragraph 0672-0673, (2018/11/26)
The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
NOVEL SUBSTITUTED PYRIDO-PIPERAZINONE DERIVATIVES AS GAMMA SECRETASE MODULATORS
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Page/Page column 78, (2014/08/06)
The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Cephalosporin derivatives
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, (2008/06/13)
The present invention relates to compounds of formula I STR1 wherein R1 is a group selected from 2-, 3-, and 4-hydroxyphenyl, 3-nitrophenyl, and 3-fluoro-4-hydroxyphenyl; as well as readily hydroyzable esters thereof, pharmaceutically acceptabl
N-Substituted pyrrolidones and their use as miticides
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, (2008/06/13)
Compounds having the formula STR1 in which R1 is C1 -C4 alkyl, R2 is selected from the group consisting of hydrogen and --CH2 X in which X is halogen, and R3 is selected from the group consisting of allyl and STR2 in which Y is selected from the group consisting of halogen and trifluoromethyl and their use as miticides are disclosed herein.
