69957-80-8

Basic information

• Product Name: CHEMBRDG-BB 9071055
• Synonyms: CHEMBRDG-BB 9071055;AKOS LT-1067X0687;N-(4-CHLOROBENZYL)-2-PROPEN-1-AMINE;N-(4-CHLOROBENZYL)PROP-2-EN-1-AMINE;UKRORGSYN-BB BBV-117207;N-(4-chlorobenzyl)-2-propen-1-amine(SALTDATA: HCl);[(4-chlorophenyl)methyl](prop-2-en-1-yl)amine hydrochloride
• CAS NO: 69957-80-8
• Molecular Formula: C₁₀H₁₂ClN
• Molecular Weight: 181.66
• Mol File: 69957-80-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 251.7°C at 760 mmHg
• Flash Point: 106°C
• Appearance: /
• Density: 1.061g/cm³
• Vapor Pressure: 0.0202mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: CHEMBRDG-BB 9071055(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 9071055(69957-80-8)
• EPA Substance Registry System: CHEMBRDG-BB 9071055(69957-80-8)

Safety Data

• Hazardous Substances Data: 69957-80-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12ClN/c1-2-7-12-8-9-3-5-10(11)6-4-9/h2-6,12H,1,7-8H2

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 107-11-9 1-amino-2-propene 
• 131480-14-3 N-[(4-chlorophenyl)methylidene]prop-2-en-1-amine 
• 188818-03-3 N-(4-chlorobenzylidene)-2,3-dibromopropylamine 
• 131480-14-3 N-allyl-1-(4-chlorophenyl)methanimine 
• 591-51-5 phenyllithium 
• 156697-68-6 2-(bromomethyl)-1-<(4-chlorophenyl)methyl>aziridine 

Downstream Products

• 1589558-46-2 (R)-2-(pent-4-enamido)-2-phenylethyl allyl(4-chlorobenzyl)carbamate 
• 1415411-24-3 3-[1-(4-chloro-benzyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-propionic acid methyl ester 
• 798542-87-7 3-[1-(4-chloro-benzyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-N-hydroxy-propionamide 
• 1415410-93-3 4-[allyl-(4-chloro-benzyl)-carbamoyl]-pent-4-enoic acid methyl ester 
• 1383423-78-6 3-(4-chlorobenzyl)-5-(iodomethyl)thiazolidine-2-thione 
• 107175-74-6 3-(4-Chloro-benzyl)-5-iodomethyl-oxazolidin-2-one 
• 55280-27-8 C₁₁H₁₁Cl₂NO 

Relevant articles and documents

Nickel(II) Catalyzed Hydroboration: A Route to Selective Reduction of Aldehydes and N-Allylimines

A cationic [(iminophosphine)nickel(allyl)]+ complex was found to be sufficiently electrophilic to activate aldehydes and N-allylimines to undergo hydroboration with pinacolborane (HBpin) under mild reaction conditions. The catalyst displayed excellent selectivity toward aldehydes in the presence of ketones. A wide variety of functional groups were tolerated, including halogens, NO2, CN, OMe, and alkenes for both aldehydes and imines. Electron-rich substrates were found to be significantly more reactive than their electron poor counterparts, a feature that was correlated to their enhanced ability to coordinate to the Lewis acidic nickel center.

SONIC HEDGEHOG MODULATORS

Sonic Hedgehog modulators and methods of use thereof are provided for.

A one-pot, three-component synthesis of thiazolidine-2-thiones

An efficient method for the synthesis of thiazolidine-2-thiones is described via regiospecific iodocyclization of an allyl amine, carbon disulfide, and iodine. Dehydrohalogenation of the iodo-derivatives gives thiazole-2(3H)-thiones. In addition, nucleoph