69976-43-8

Upstream product

• 533-58-4 2-Iodophenol 
• 33577-99-0 2-ethynyl-benzoic acid methyl ester 
• 98437-24-2 benzofuran-2-boronic acid 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 271-89-6 1-benzofurane 
• 67-56-1 methanol 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 70340-04-4 (2-hydroxybenzyl)triphenylphosphonium bromide 
• 4397-55-1 phthalic monoacid monomethyl ester chloride 
• 129503-22-6 2-(2-methoxycarbonylbenzoyloxy)benzyltriphenylphosphonium bromide 

Downstream Products

• 1025934-53-5 2-Benzofuran-2-yl-benzoyl chloride 
• 121668-46-0 2-(benzofuran-2-yl)benzoic acid 

Relevant academic research and scientific papers

Synthesis of 2-Arylbenzo[b]furans via Copper(I)-Catalyzed Coupling of o-Iodophenols and Aryl Acetylenes

(Equation Presented) We report a copper(I)-catalyzed procedure for the synthesis of 2-arylbenzo[b]furans. This protocol can be used to synthesize a variety of 2-arylbenzo[b]furans in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives, and is palladium-free.

Dioxazolones as masked ester surrogates in the Pd(ii)-catalyzed direct C-H arylation of 6,5-fused heterocycles

A simple and effective Pd(ii)-catalyzed regioselective C(2)-H arylation of 6,5-fused heterocycles with dioxazolones as a masked ester surrogate under mild conditions is reported. The significance of the arylation is highlighted by the new reactivity demonstrated in dioxazolones via proximal C-H activation of the cyclic carbonate of the hydroxamic acid functionality under protic conditions.

An organoelectro luminescent compounds and organoelectro luminescent device using the same

The present invention relates to organic light emitting compounds represented by chemical formula 1-1 to chemical 1-4, and to an organic electroluminescent device comprising the same. an organic electroluminescent device applying the organic light emittin

Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts

A copper(I)-catalyzed procedure for the synthesis of benzo[b]heterocycles. This protocol can be used to synthesize a variety of 2-arylbenzo[b]furans and indoles in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives and is palladium-free.

Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations

This article describes the design, optimisation and development of a Suzuki cross-coupling protocol mediated by an efficient palladium-en-capsulated catalyst (Pd EnCat) under microwave irradiation. The methodology has been used in both batch mode for classical library preparation and in continuous-flow applications furnishing multigram quantities of material. Described is a method that uses direct focused microwave heating whilst applying an external cooling source. This enables a lower than normal bulk temperature to be maintained throughout the reaction period leading to significant improvements in the overall yield and purity of the reaction products. Additional aspects of this novel heating protocol are discussed in relation to the prolonged lifetime and enhanced reactivity of the immobilised catalyst system.

Copper(I)-catalyzed coupling of terminal acetylenes with aryl or vinyl halides

Synthetic protocols using copper(I) catalysts for the formation of diaryl acetylenes, 1,3-enynes, benzofurans and indoles are described. Georg Thieme Verlag Stuttgart.

Synthetic Routes to 2-(2-Benzofuranyl)benzoic Acids and their Cyclization into Benzindenofuran-10-ones

The benzindenofuran-10-ones 1 were prepared by the intramolecular cyclization of the 2-(2-benzofuranyl)benzoic acids, 2, the unequivocal routes to which are described herein.Various synthetic methods to these acids were tested, as well as the methods to cyclize them.