70001-47-7 Usage
Description
N-butyl-3-nitrobenzamide is a chemical compound belonging to the aromatic amides class, with the molecular formula C12H14N2O3. It features a butyl group attached to the nitrogen atom of a 3-nitrobenzamide molecule, giving it a yellow crystalline appearance. N-butyl-3-nitrobenzamide is widely recognized for its role as an intermediate in the synthesis of various organic compounds and for its applications in the production of dyes, pharmaceuticals, and agrochemicals. Its potential in medicinal chemistry is also noteworthy due to its intriguing biological activities and pharmacological properties.
Uses
Used in Organic Synthesis:
N-butyl-3-nitrobenzamide serves as a crucial intermediate in the synthesis of a range of organic compounds. Its unique structure allows for the creation of diverse chemical entities, making it a valuable component in organic chemistry.
Used in Dye Production:
In the dye industry, N-butyl-3-nitrobenzamide is utilized for the production of various dyes. Its chemical properties contribute to the color and stability of the dyes, enhancing their performance in different applications.
Used in Pharmaceutical Development:
N-butyl-3-nitrobenzamide plays a significant role in the pharmaceutical sector, where it is employed in the development of new drugs. Its biological activities and pharmacological properties make it a promising candidate for medicinal applications.
Used in Agrochemicals:
N-butyl-3-nitrobenzamide also finds use in the agrochemical industry, where it is involved in the production of various agrochemical products. Its contribution to the effectiveness and quality of these products is essential for agricultural applications.
Used in Medicinal Chemistry Research:
Due to its interesting biological activities and pharmacological properties, N-butyl-3-nitrobenzamide is a subject of interest in medicinal chemistry research. Scientists explore its potential for developing new therapeutic agents and understanding its mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 70001-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,0,0 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70001-47:
(7*7)+(6*0)+(5*0)+(4*0)+(3*1)+(2*4)+(1*7)=67
67 % 10 = 7
So 70001-47-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O3/c1-2-3-7-12-11(14)9-5-4-6-10(8-9)13(15)16/h4-6,8H,2-3,7H2,1H3,(H,12,14)
70001-47-7Relevant articles and documents
Radical-mediated divergent cyclization of benzamides toward perfluorinated or cyanated isoquinolinediones
Deng, You-Lin,Tang, Shi,Ding, Guo-Liang,Wang, Ming-Wei,Li, Jie,Li, Zeng-Zeng,Yuan, Li,Sheng, Rui-Long
supporting information, p. 9348 - 9353 (2016/10/13)
A simple and efficient copper-controlled divergent cyclization of benzamides, which leads to perfluorinated or cyanated isoquinolinediones, is developed. In the presence of AIBN, methacryloyl benzamides with perfluoroalkyl iodides undergo cascade radical addition/cyclization to afford perfluoroinated isoquinolinediones as the major product under metal-free conditions, whereas the use of CuI (10 mol%) is able to redirect the cyclization to yield isoquinolinediones bearing an α-cyano quaternary carbon center. The cyclization features controllable divergent synthesis and a broad substrate scope as well as highly practical reaction conditions, thereby making this strategy a highly attractive means to fluorinate or cyanate isoquinolinediones.
Aminocarbonylations employing Mo(CO)6 and a bridged two-vial system: Allowing the use of nitro group substituted aryl iodides and aryl bromides
Nordeman, Patrik,Odell, Luke R.,Larhed, Mats
, p. 11393 - 11398 (2013/02/23)
A bridged two-vial system aminocarbonylation protocol where Mo(CO) 6 functions as an external in situ solid source of CO has been developed. For the first time both nitro group containing aryl/heteroaryl iodides and bromides gave good to excellent yields in the Mo(CO) 6-mediated and palladium(0)-catalyzed conversion to benzamides, while the identical one-vessel protocol afforded extensive reduction of the nitro functionality. The above-mentioned bridged two-compartment protocol furnished good results with both primary amines and secondary amines and sluggish aniline nucleophiles at 65-85 C reaction temperatures.
3-(2′-Bromopropionylamino)-benzamides as novel S-phase arrest agents
Hu, Laixing,Li, Zhuo-rong,Li, Jian-Nong,Qu, Jinrong,Jiang, Jian-Dong,Boykin, David W.
, p. 6847 - 6852 (2008/09/16)
We report the synthesis, antiproliferative activity, and SAR of novel 3-(2′-bromopropionylamino)-benzamides. Many of the benzamide compounds showed potent cytotoxicities against Molt-3 leukemia cells. Several compounds exihibited cytotoxicities (under 6.5