70006-37-0

Basic information

• Product Name: 2-Pyrrolidinone, 3-hydroxy-4,4-dimethyl-1-phenyl-
• CAS NO: 70006-37-0
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• Mol File: 70006-37-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinone, 3-hydroxy-4,4-dimethyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone, 3-hydroxy-4,4-dimethyl-1-phenyl-(70006-37-0)
• EPA Substance Registry System: 2-Pyrrolidinone, 3-hydroxy-4,4-dimethyl-1-phenyl-(70006-37-0)

Safety Data

• Hazardous Substances Data: 70006-37-0(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 79-50-5 pantolactone 
• 565430-86-6 2,4-dihydroxy-N-phenyl-3,3-dimethylbutyramide 
• 100618-94-8 N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide 
• 43180-77-4 N-heptyl-2,4-dihydroxy-3,3-dimethylbutyramide 
• 4417-86-1 (R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide 

Downstream Products

• 615252-88-5 (S)-3-acetoxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone 
• 169221-12-9 (S)-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone 
• 1508320-10-2 C₃₀H₂₉NO₂Si 
• 169221-13-0 (R)-3-hydroxy-4,4-dimethyl-1-phenylpyrrolidin-2-one 
• 247248-94-8 4,4-dimethyl-1-phenylpyrrolidine-2,3-dione 

Relevant articles and documents

Stereoselective synthesis of both enantiomers of N-Boc-α-aryl- γ-aminobutyric acids

Esterification of racemic α-aryl-β-cyanopropionic acid chlorides with either (R)- or (S)-N-phenylpantolactam as the chiral auxiliary in the presence of Et3N resulted in the predominant formation of (αR,3′R)- or (αS,3′S)-configured pantolactam c

(R)- and (S)-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone by lipase-catalyzed resolution of the racemic mixture: New chiral auxiliaries related to pantolactone

(R)- and (S)-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone (R)- and (S)-1 have been prepared by lipase-catalyzed enantioselective acetylation of (S)-1 from rac-1 with vinyl acetate. Controlled hydrolysis of the acetate (S)-2 gave (S)-1. The configuration of (R)-1 and its p-bromobenzoate (R)-3 were established by X-ray diffraction analysis.