70007-07-7

Basic information

• Product Name: [5-chloro-2-(2,4-dichlorophenoxy) phenoxy]-acetic acid methyl ester
• Synonyms: [5-chloro-2-(2,4-dichlorophenoxy) phenoxy]-acetic acid methyl ester
• CAS NO: 70007-07-7
• Molecular Weight: 361.609
• Mol File: 70007-07-7.mol

Chemical Properties

• CAS DataBase Reference: [5-chloro-2-(2,4-dichlorophenoxy) phenoxy]-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [5-chloro-2-(2,4-dichlorophenoxy) phenoxy]-acetic acid methyl ester(70007-07-7)
• EPA Substance Registry System: [5-chloro-2-(2,4-dichlorophenoxy) phenoxy]-acetic acid methyl ester(70007-07-7)

Safety Data

• Hazardous Substances Data: 70007-07-7(Hazardous Substances Data)

Upstream product

• 3380-34-5 triclosan 
• 96-34-4 methyl chloroacetate 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 1146530-39-3 [5-chloro-2-(2,4-dichlorophenoxy) phenoxy]-acetic acid 
• 1146530-40-6 [5-Chloro-2-(2,4-dichloro-phenoxy)-phenoxy]-acetic acid methoxy carbonyl methyl ester 

Relevant articles and documents

Synthesis and herbicidal activities of aryloxyacetic acid derivatives as HPPD inhibitors

A series of aryloxyacetic acid derivatives were designed and synthesized as 4-hydoxyphenylpyruvate dioxygenase (HPPD) inhibitors. Preliminary bioassay results reveal that these derivatives are promising Arabidopsis thaliana HPPD (AtHPPD) inhibitors, in particular compounds I12 (Ki = 0.011 μM) and I23 (Ki = 0.012 μM), which exhibit similar activities to that of mesotrione, a commercial HPPD herbicide (Ki = 0.013 μM). Furthermore, the newly synthesized compounds show significant greenhouse herbicidal activities against tested weeds at dosages of 150 g ai/ha. In particular, II4 exhibited high herbicidal activity for pre-emergence treatment that was slightly better than that of mesotrione. In addition, compound II4 was safe for weed control in maize fields at a rate of 150 g ai/ha, and was identified as the most potent candidate for a novel HPPD inhibitor herbicide. The compounds described herein may provide useful guidance for the design of new HPPD inhibiting herbicides and their modification.

Functionalized biodegradable triclosan monomers and oligomers for controlled release

This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.

FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE

This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.

Selective enzyme-linked immunosorbent assay for triclosan. Application to wastewater treatment plant effluents

A sensitive and highly selective enzyme-linked immunosorbent assay was developed for triclosan, one of the most common bactericides in personal care products, which is also considered as an emerging contaminant, given its presence in the effluents of sewage and wastewater treatment plants. From synthesized haptens, polyclonal rabbit antibodies against triclosan were raised. The best ELISA immunoassay was based on an antibody-coated format, yielding a detection limit of 0.03 μg L-1, an I50 of 3.85 μg L-1, and a dynamic range from 0.22 to 42.16 μg L-1, with little or no cross-reactivity (a screening method to quantify triclosan in surface water and in wastewaters. After C18 solid-phase extraction, nanogram per liter concentrations were determined in effluents of urban wastewater treatment plants. The satisfactory recoveries achieved as well as the agreement between immunochemical and chromatographic methods (GC-MS) indicate its potential for either screening or laboratory quantification.