Welcome to LookChem.com Sign In|Join Free
  • or

3380-34-5

Post Buying Request

3380-34-5 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
High purity Triclosan 3380-34-5 /manufacturer/low price/high quality/in stock
Cas No: 3380-34-5
USD $ 13.0-14.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Bactericides Triclosan (TCS) 3380-34-5
Cas No: 3380-34-5
No Data 1 Gram 1 Metric Ton/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Triclosan
Cas No: 3380-34-5
No Data 1 Gram 2000 Metric Ton/Month UNION PHARMPRO CO.,LTD Contact Supplier
White crystalline powder triclosan 99% CAS:3380-34-5
Cas No: 3380-34-5
No Data 1 Gram 100 Kilogram/Day Shaanxi wuzhiyuan biotech co.,LTD Contact Supplier
Triclosan
Cas No: 3380-34-5
No Data 1 Kilogram 1000 Metric Ton/Month Haihang Industry Co.,Ltd. Contact Supplier
High purity Triclosan with best price and good quality
Cas No: 3380-34-5
No Data 10 Gram 200 Kilogram/Week Hubei Jusheng Technology Co., Ltd., Contact Supplier
High quality Triclosan supplier in China
Cas No: 3380-34-5
No Data 1 Kilogram 10 Metric Ton/Month Simagchem Corporation Contact Supplier
Triclosan
Cas No: 3380-34-5
No Data 1 Metric Ton 500 Metric Ton/Month Anyang General Chemical Co.,Ltd. Contact Supplier
Triclosan
Cas No: 3380-34-5
No Data 1 Kilogram 3000 Metric Ton/Year Hefei TNJ chemical industry co.,ltd Contact Supplier
Triclosan CAS#3380-34-5
Cas No: 3380-34-5
No Data 1 Kilogram 500 Metric Ton/Year ORCHID CHEMICAL SUPPLIES LTD Contact Supplier

3380-34-5 Usage

Brand name

Stri-Dex Cleansing Bar (Sterling Health U.S.A.); Stri-Dex Face Wash (Sterling Health U.S.A.).

Uses

1. It can be used as antiseptic and fungicide and applied to cosmetics, emulsions and resins; also can be used for the manufacture of disinfection medicated soap. The LD50 of mice subject to oral administration of this product is 4g/kg.
2. It can be used for the production of top-grade daily chemical product, the disinfectants of medical instrument as well as diet instrument as well as the preparation of the anti-bacterial, deodorant finishing agent of fabric.
3. It can also be applied to biochemical studies. It is a kind of broad-spectrum antimicrobial agents which inhibit the type II fatty acid synthase (FAS-II) of bacteria and parasites, and also inhibits the mammalian fatty acid synthase (FASN), and may also have anticancer activity

Production method

1. Take 2, 4-dichloro-phenol as the raw material; use 2,4-dichloro-phenol to react with potassium hydroxide to generate dichlorophenol potassium which further reacts with 2,5-dichloro-nitrobenzene in the catalysis of copper for generation of 2,4,4-trichloro-2'-nitro diphenyl ether. It is further reduced by iron powder to generate 2, 4, 4-trichloro-2'-amino diphenyl ether, and then further went through diazotization hydrolysis to obtain the product.
2. Take o-methoxyphenol as the raw material: have potassium hydroxide powder reacted with guaiacol to generate guaiacol potassium. Apply reaction between bromobenzene and methoxy ether, together with chlorine for chlorination to obtain 2, 4, 4’-trichloro-2'-methoxydiphenyl ether. Take AICI3 as hydrolysis catalyst to generate 2,4,4'-trichloro-2'-hydroxydiphenyl ether.

Definition

ChEBI: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodo ants as well as in household items such as plastic chopping boards, sports equipment and shoes.

Disinfectants

Triclosan is an efficient broad-spectrum topical antimicrobial disinfectant which is normally white or off-white crystalline powder. It has a slightly phenolic odor. It is insoluble in water but easily soluble in organic solvents and alkali. It has a relative stable chemical property and is heating-resistant and also resistant to acid and alkali hydrolysis without generating any symptoms of the toxicity and environmental pollution. It is internationally recognized as a fungicide variety with specific efficacy. It can kill bacteria such as Staphylococcus aureus, Escherichia coli and fungi such as Candida albicans. It also has an inhibitory effect on the virus (e.g., hepatitis B virus, etc.) while being able to protect the beneficial bacteria. The mechanism of action of triclosan is as below: it is first adsorbed on the bacterial cell wall and then further penetrates through the cell wall and has reaction with the lipid and protein in the cytoplasm, and thus resulting in protein denaturation which further kill the bacteria. Currently it has been widely applied to highly-efficient medicated soap (health soap, health lotion), removing underarm odor (foot aerosol), hand sanitizer, wound disinfectant sprays, medical equipment disinfectants, hygiene cleanser (cream), and air fresheners and refrigerator deodorants and some other daily chemicals. It is also used for the cleaning of the health fabric and the anti-corrosion treatment of plastics. Its high purity version can be added to the toothpaste and mouthwash for treatment of gingivitis, periodontitis and oral ulcers. The State content must not exceed 0.3%.

Chemical Properties

Solid

Toothpaste Standard

The national standard of the toothpaste used in China is the new national standard of toothpaste (GB8372-2008) implemented on February 1, 2009. Compared with the 2001 version of toothpaste standard, the new national standard has been supplemented and adjusted in various aspects. In the new national standard of toothpaste, the prohibited or restricted ingredients include nearly 1,500 kinds, including diethylene glycol and triclosan. The provision of diethylene glycol is that it is not allowed to artificially add it to the raw materials, such as being introduced as impurities. Its content in the toothpaste should not exceed 0.1%. Triclosan were listed as being allowable preservatives but with the usage amount not exceeding 0.3%. The new national standard has ruled that the fluorine content of the fluoride-containing toothpaste should be within the range of 0.04%-0.15%, and the fluoride content should be within the range of 0.05% to 011% for children fluoride-containing toothpaste.
The above information is edited by the chemicalbook of Dai Xiongfeng.

Chemical Properties

It is colorless and long needle-like crystals with a melting point being around 54-57.3 ℃ (60-61 ℃). It is slightly soluble in water and soluble in ethanol, acetone, ethyl ether and alkali solution. It has a chloro-phenol odor.

Uses

anticonvulsant

Uses

Bacteriostat and preservative for cosmetic and detergent preparations.

Carcinogenicity

In 2004, a teacher (Dr. Peter Vikesland) from the Virginia Tech University (US) had found from the experiments that the reaction between the triclosan-containing product and the chlorine-containing tap water containing can generate a substance known as "chloroform aryl", that is, chloroform (chemical name: trichloromethane) which is a colorless, volatile liquid with a special sweetness. Upon exposure to light, it will be oxidized to generate hydrogen chloride and phosgene. It had been once used as an anesthetic. Animal experiments have found that this substance will do harm to the heart and liver with mild teratogenicity and can induce the liver cancer of mice. However, so far no studies on the human carcinogenicity have been reported. For insurance purposes, both the International Cancer Research Centre and the United States have already has the chloroform be listed as suspected carcinogens to the human body.

Uses

Used as bacteriostat and preservative for cosmetic and detergent compositions. Antiseptic, disinfectant.

3380-34-5 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1682206)  Triclosan  United States Pharmacopeia (USP) Reference Standard 3380-34-5 1682206-200MG 4,588.74CNY Detail
Alfa Aesar (L18655)  5-Chloro-2-(2,4-dichlorophenoxy)phenol, 99%    3380-34-5 500g 5080.0CNY Detail
Alfa Aesar (L18655)  5-Chloro-2-(2,4-dichlorophenoxy)phenol, 99%    3380-34-5 100g 1409.0CNY Detail
Alfa Aesar (L18655)  5-Chloro-2-(2,4-dichlorophenoxy)phenol, 99%    3380-34-5 10g 256.0CNY Detail

3380-34-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name triclosan

1.2 Other means of identification

Product number -
Other names TRICLOSAN USP

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3380-34-5 SDS

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields