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GLY-ASP-ASP-ASP-ASP-LYS BETA-NAPHTHYLAMIDE is a peptide derivative composed of the amino acids glycine (GLY), aspartic acid (ASP), and lysine (LYS), along with a beta-naphthylamide moiety. GLY-ASP-ASP-ASP-ASP-LYS BETA-NAPHTHYLAMIDE is widely utilized in biochemical and pharmaceutical research as a substrate for determining aspartyl protease activity, specifically for characterizing enzymes such as cathepsins and presenilins. The beta-naphthylamide group acts as a reporter molecule, emitting a fluorescent signal upon protease cleavage, which enables the detection and quantification of enzymatic activity.

70023-02-8

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70023-02-8 Usage

Uses

Used in Biochemical Research:
GLY-ASP-ASP-ASP-ASP-LYS BETA-NAPHTHYLAMIDE is used as a substrate for the determination of aspartyl protease activity, allowing researchers to study the function and regulation of these enzymes in various biological processes.
Used in Pharmaceutical Research:
In the pharmaceutical industry, GLY-ASP-ASP-ASP-ASP-LYS BETA-NAPHTHYLAMIDE serves as a valuable tool for the characterization of enzymes like cathepsins and presenilins, which are implicated in numerous diseases. Understanding their activity and role in disease pathways can aid in the development of targeted therapies.
Used in Enzyme Activity Detection and Quantification:
GLY-ASP-ASP-ASP-ASP-LYS BETA-NAPHTHYLAMIDE is used as a reporter molecule in assays, where the fluorescent signal produced upon cleavage by the protease enables the detection and quantification of enzymatic activity. This is crucial for assessing enzyme function and potential drug interactions.
Used in Disease Research:
Due to its specific reactivity with aspartyl proteases, GLY-ASP-ASP-ASP-ASP-LYS BETA-NAPHTHYLAMIDE is an important tool for studying the role of these enzymes in various diseases. This can provide insights into disease mechanisms and contribute to the development of therapeutic strategies targeting these enzymes.

Check Digit Verification of cas no

The CAS Registry Mumber 70023-02-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,0,2 and 3 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 70023-02:
(7*7)+(6*0)+(5*0)+(4*2)+(3*3)+(2*0)+(1*2)=68
68 % 10 = 8
So 70023-02-8 is a valid CAS Registry Number.
InChI:InChI=1/C34H44N8O14/c35-10-4-3-7-20(30(52)37-19-9-8-17-5-1-2-6-18(17)11-19)39-32(54)22(13-27(46)47)41-34(56)24(15-29(50)51)42-33(55)23(14-28(48)49)40-31(53)21(12-26(44)45)38-25(43)16-36/h1-2,5-6,8-9,11,20-24H,3-4,7,10,12-16,35-36H2,(H,37,52)(H,38,43)(H,39,54)(H,40,53)(H,41,56)(H,42,55)(H,44,45)(H,46,47)(H,48,49)(H,50,51)/t20-,21-,22?,23-,24-/m0/s1

70023-02-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(2-aminoacetyl)amino]-4-[[1-[[1-[[1-[[6-amino-1-(naphthalen-2-ylamino)-1-oxohexan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70023-02-8 SDS

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