70031-86-6

Basic information

• Product Name: 4-Phenyl-2-(3-pyridyl)thiazole, 97%
• Synonyms: 4-Phenyl-2-(3-pyridyl)thiazole, 97%;Pyridine, 3-(4-phenyl-2-thiazolyl)-;4-Phenyl-2-(pyridin-3-yl)thiazole;4-phenyl-2-pyridin-3-yl-1,3-thiazole
• CAS NO: 70031-86-6
• Molecular Formula: C₁₄H₁₀N₂S
• Molecular Weight: 238.3076
• Mol File: 70031-86-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 52-56℃
• Boiling Point: 437.8°C at 760 mmHg
• Flash Point: 211.8°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.633
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Phenyl-2-(3-pyridyl)thiazole, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenyl-2-(3-pyridyl)thiazole, 97%(70031-86-6)
• EPA Substance Registry System: 4-Phenyl-2-(3-pyridyl)thiazole, 97%(70031-86-6)

Safety Data

• Hazardous Substances Data: 70031-86-6(Hazardous Substances Data)

Usage

General Description

4-Phenyl-2-(3-pyridyl)thiazole, 97% is a chemical compound that is important in the field of pharmaceuticals and organic synthesis. It is a thiazole derivative with the molecular formula C15H11N3S, and it is commonly used as a building block for the synthesis of various biologically active compounds. 4-Phenyl-2-(3-pyridyl)thiazole, 97% is known for its potent antibacterial, antifungal, and anti-inflammatory properties, making it a valuable ingredient in developing new drugs and medications. With a high purity of 97%, this chemical is widely used in research laboratories and pharmaceutical industries for drug discovery and development purposes.

InChI:InChI=1/C14H10N2S/c1-2-5-11(6-3-1)13-10-17-14(16-13)12-7-4-8-15-9-12/h1-10H

Upstream product

• 4621-66-3 thionicotinamide 
• 70-11-1 α-bromoacetophenone 
• 100-42-5 styrene 
• 4636-16-2 iodoacetophenone 

Downstream Products

• 145737-98-0 3-(4-phenylthiazol-2-yl)pyridine-N-oxide 
• 92165-08-7 4-(2-pyridin-3-yl-thiazol-4-yl)-aniline 
• 25179-43-5 1,3-bis-[4-(2-pyridin-3-yl-thiazol-4-yl)-phenyl]-thiourea 
• 25021-44-7 3-[4-(4-nitro-phenyl)-thiazol-2-yl]-pyridine 

Relevant articles and documents

Solid state thiazole-based fluorophores: Promising materials for white organic light emitting devices

A facile and more efficient solvent-free mechanochemical synthetic route has been developed for the synthesis of a series of solid state white light emissive thiazole-based donor-acceptor (D-A) type fluorophores, 2-(3-pyridyl)/2-aminothiazoles from ω-bromomethylketones and pyridine-3-carbothioamide/thiourea in the presence of silica-supported HClO4 as a reusable solid Br?nsted acid catalyst at RT. The photophysical and electrochemical properties of these compounds have been derived. Most of the studied D-A type solid thiazole-based fluorophores emitted white light and it can be tuned from warm - ideal - cold white light by introduction of a variety of substituents at 4th position of 2-(3-pyridyl)/2-aminothiazoles. Further, HOMO and LUMO energy levels of the titled compounds are found to be in the range ?5.52 eV to ?5.72 eV and ?1.84 eV to ?2.45 eV, respectively. The lifetimes of these levels of thiazole-based fluorophores have been determined through luminescence decay curves and are found to be in the range of 7.7–11 μs. The photophysical and electrochemical properties of the synthesized thiazole-based fluorophores indicate that the compounds could be promising materials for white organic light emitting devices.

Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes

A range of heterocycles, namely thiazoles, imidazoles, imidazopyridines, thiazolidines and dimethoxyindoles, have been synthesised directly from alkenes via a two-step ketoidoination/cyclisation protocol. The alkene starting materials are themselves readily accessible using many different and well-established approaches, and allow access to a variety of heterocycles with excellent yields and regioselectivity.

Chemotherapy of tuberculosis. IX. Synthesis and screening of new thiazolyl thiocarbanilides.

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