700381-18-6 Usage
Description
5-Fluoro-2-methoxybenzyl bromide 97, with the molecular formula C8H8BrFO, is a colorless to yellow liquid chemical compound. It has a molecular weight of 215.053 g/mol and is known for its reactivity in organic synthesis, particularly for introducing the 5-fluoro-2-methoxybenzyl group into various compounds. Due to its potential for causing irritation and harm, it must be handled with care and proper safety protocols, including the use of personal protective equipment and working in a well-ventilated area.
Uses
Used in Organic Synthesis:
5-Fluoro-2-methoxybenzyl bromide 97 is used as a reagent in organic synthesis for its ability to introduce the 5-fluoro-2-methoxybenzyl group into different compounds. This property makes it valuable in the creation of new chemical entities with specific functional groups, which can be utilized in various applications across different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Fluoro-2-methoxybenzyl bromide 97 is used as an intermediate in the synthesis of various drug molecules. Its ability to introduce the 5-fluoro-2-methoxybenzyl group can contribute to the development of new pharmaceutical compounds with improved therapeutic properties.
Used in Chemical Research:
5-Fluoro-2-methoxybenzyl bromide 97 is also used in chemical research as a tool to study the reactivity and properties of the 5-fluoro-2-methoxybenzyl group. Researchers can use this compound to explore its potential applications and understand the mechanisms of reactions involving this functional group.
Used in Material Science:
In material science, 5-Fluoro-2-methoxybenzyl bromide 97 can be used as a precursor to develop new materials with specific properties. The introduction of the 5-fluoro-2-methoxybenzyl group can lead to the creation of materials with unique characteristics, such as improved stability, reactivity, or selectivity, which can be applied in various technological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 700381-18-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,0,3,8 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 700381-18:
(8*7)+(7*0)+(6*0)+(5*3)+(4*8)+(3*1)+(2*1)+(1*8)=116
116 % 10 = 6
So 700381-18-6 is a valid CAS Registry Number.
InChI:InChI:1S/C8H8BrFO/c1-11-8-3-2-7(10)4-6(8)5-9/h2-4H,5H2,1H3
700381-18-6Relevant articles and documents
Synthesis of Phenanthridines through Palladium-Catalyzed Cascade Reaction of 2-Halo-N-Ms-arylamines with Benzyl Halides/Sulfonates
Yang, Si-Yi,Han, Wen-Yong,Zhang, Ding-Lei,Zhou, Xiao-Jian,Bai, Mei,Cui, Bao-Dong,Wan, Nan-Wei,Yuan, Wei-Cheng,Chen, Yong-Zheng
, p. 996 - 1003 (2017/02/15)
An efficient palladium-catalyzed nucleophilic substitution/C–H activation/aromatization cascade reaction between readily available 2-halo-N-Ms-arylamines (Ms = methanesulfonyl) and benzyl halides/sulfonates has been described. A wide variety of phenanthridines were synthesized in a one-pot fashion in moderate to high yields (37–86 %). Notably, this method provides a straightforward, facile approach for the synthesis of phenanthridines. The practicality was further substantiated by successfully carrying out a gram-scale preparation.
NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES
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Page/Page column 37, (2010/01/29)
[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution] The present invention provides nitrogen-containing fused ring derivatives represented by the following general formula (I) which has a GnRH antagonistic activity, prodrugs, salts, pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A and B are independently aryl or heteroaryl; RA and RB are independently halogen, cyano, alkyl, alkylsulfonyl, -OW1, -SW1, -COW2, -NW3W4, -SO2NW3W4, aryl, etc.; RC is H or alkyl; E is oxygen atom, etc.; U is single bond or alkylene; and X is Y, -CO-Y, -SO2-Y -S-(alkylene)-Y, -O-(alkylene)-Y, -SO2-(alkylene)-Y, etc.; Y is Z or amino, etc.; and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.
MORPHOLINE DERIVATIVES AS NOREPINEPHRINE REUPTAKE INHIBITORS
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Page/Page column 42-43, (2008/06/13)
Compounds of the general formula (I) are inhibitors of the reuptake of norepinephrine. As such, they may be useful for the treatment of disorders of the central and/or peripheral nervous system.