78550-50-2

Upstream product

• 50-00-0 formaldehyd 
• 371-41-5 4-Fluorophenol 
• 19415-51-1 5-fluoro-2-methoxybenzaldehyde 
• 700381-18-6 2-(bromomethyl)-4-fluoro-1-methoxybenzene 
• 426831-32-5 (5-fluoro-2-methoxyphenyl)methanol 

Downstream Products

• 71319-34-1 C₁₃H₈F₂N₂O₆ 
• 83153-63-3 Acetic acid 2-(2-acetoxy-5-fluoro-benzyl)-4-fluoro-phenyl ester 
• 78563-30-1 C₂₇H₂₀F₄O₄ 
• 83143-19-5 Acetic acid 2-(2-acetoxy-5-fluoro-benzoyl)-4-fluoro-phenyl ester 
• 78563-09-4 1-[3-(3-Acetyl-5-fluoro-2-hydroxy-benzyl)-5-fluoro-2-hydroxy-phenyl]-ethanone 
• 83143-05-9 1-[3-(3-Acetyl-5-fluoro-2-hydroxy-benzoyl)-5-fluoro-2-hydroxy-phenyl]-ethanone 
• 83143-09-3 1-{3-[1-(3-Acetyl-5-fluoro-2-hydroxy-phenyl)-1-hydroxy-ethyl]-5-fluoro-2-hydroxy-phenyl}-ethanone 
• 83143-22-0 1,1-bis(2-acetoxy-5-fluorophenyl)ethanol 
• 78563-31-2 Acetic acid 2-[2-acetoxy-3-(2-acetoxy-5-fluoro-benzyl)-5-fluoro-benzyl]-6-(2-acetoxy-5-fluoro-benzyl)-4-fluoro-phenyl ester 
• 78563-34-5 Acetic acid 2-[2-acetoxy-3-(2-acetoxy-5-fluoro-benzoyl)-5-fluoro-benzoyl]-6-(2-acetoxy-5-fluoro-benzoyl)-4-fluoro-phenyl ester 

Relevant academic research and scientific papers

One-step novel synthesis of methylene bisphenols and methylene bisnaphthols using Lewis acid mediated rearrangement

Mono- and di-substituted isomeric methylene bisphenols and methylene bisnaphthols have been synthesized by rearrangement of the corresponding O-methoxyacetyl derivatives of phenols and naphthols, respectively, in presence of aluminium chloride under dry conditions. The chemistry observed is different from the usual Fries rearrangement reaction and involves an intermolecular rearrangement. The reactions reported here also reflect the influence of substituents present in the substrate as is supported by the substitution of the bridging methylene at a position meta to the phenolic hydroxyl in some of the minor products formed along-side the majorly formed ortho substituted products.

ORGANIC COMPOUNDS

A compound of formula (I); in free or pharmaceutically acceptable salt form, where R1, R2, R3, R4, R5, m, n, w, X, Y and Q have the meanings as indicated in the specification, are useful for treating conditions mediated by the CRTh2 receptor, especially inflammatory or obstructive airways diseases.

The Synthesis of Polyfunctional Aromatic Ring Systems. Structural Analogues of Phloroglucides, Aranciamycin, Cryptosporin and Terramycin

The synthesis of the title compounds is described.Some of the compounds prepared were found to be active against a number of pathogenic microorganisms in vitro.