7004-12-8 Usage
Uses
Used in Pharmaceutical Industry:
FMOC-ARG(PBF)-OPFP is used as a building block for the synthesis of peptides and proteins. Its unique chemical properties make it a valuable tool in the development of new drugs and therapies.
Used in Diagnostics:
FMOC-ARG(PBF)-OPFP is used as a diagnostic aid in the determination of pituitary function. It can also be used to measure the levels of certain enzymes, such as argininosuccinate synthetase, which is involved in the biosynthesis of arginine.
Used in Detoxification:
FMOC-ARG(PBF)-OPFP can be used as an ammonia detoxicant, helping to remove excess ammonia from the body and prevent the buildup of toxic levels.
Used in Cosmetics:
FMOC-ARG(PBF)-OPFP is used as an ingredient in the cosmetics industry due to its antistatic, masking, hair, and skin-conditioning properties.
Used in Food Industry:
FMOC-ARG(PBF)-OPFP is used to improve the biological quality of the total protein in food products that contain naturally occurring proteins. It is also used as a nutrient and dietary supplement.
Used in Research:
FMOC-ARG(PBF)-OPFP is used in research to study the role of arginine in various biological processes, such as cell signaling, immune function, and wound healing.
Used in Treatment of Specific Conditions:
FMOC-ARG(PBF)-OPFP has been found to be effective in treating various conditions, such as lung inflammation, asthma, growth hormone stimulation, MELAS syndrome, sepsis, alcoholic hepatitis, advanced cirrhosis, pre-eclampsia, hypertension, erectile dysfunction, and anxiety.
Biological Functions
Arginine plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, and the release of hormones. The benefits and functions attributed to oral supplementation of L-arginine include: Precursor for the synthesis of nitric oxide (NO) Reduces healing time of injuries (particularly bone) Quickens repair time of damaged tissue Helps decrease blood pressure in clinical hypertensive subjects.
Synthesis Reference(s)
Tetrahedron, 44, p. 805, 1988 DOI: 10.1016/0040-4039(96)01716-9Tetrahedron Letters, 37, p. 7557, 1996 DOI: 10.1016/0040-4039(96)01716-9Chemical and Pharmaceutical Bulletin, 29, p. 2825, 1981 DOI: 10.1248/cpb.29.2825
Check Digit Verification of cas no
The CAS Registry Mumber 7004-12-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,0 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7004-12:
(6*7)+(5*0)+(4*0)+(3*4)+(2*1)+(1*2)=58
58 % 10 = 8
So 7004-12-8 is a valid CAS Registry Number.
InChI:InChI=1/C40H39F5N4O7S/c1-19-20(2)36(21(3)26-17-40(4,5)56-34(19)26)57(52,53)49-38(46)47-16-10-15-28(37(50)55-35-32(44)30(42)29(41)31(43)33(35)45)48-39(51)54-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,48,51)(H3,46,47,49)/t28-/m0/s1
7004-12-8Relevant academic research and scientific papers
New conjugates of muramyl dipeptide and nor-muramyl dipeptide linked to tuftsin and retro-tuftsin derivatives significantly influence their biological activity
Dzierzbicka, Krystyna,Wardowska, Anna,Rogalska, Ma?gorzata,Trzonkowski, Piotr
body text, p. 217 - 223 (2012/08/29)
The synthesis and biological activity of new conjugates of muramyl dipeptide (MDP) and nor-muramyl dipeptide (nor-MDP) with tuftsin and retro-tuftsin derivatives containing isopeptide bond between e-amino group of lysine and carboxyl group of simple amino
A NOVEL ENZYME "Nα-BENZYLOXYCARBONYL AMINO ACID URETHANE HYDROLASE II" FROM LACTOBACILLUS FERMENTI 36 ATCC 9338
Matsumura, Eiko,Shin, Takashi,Murao, Sawao,Yamamoto, Eiko,Kawano, Tatsu
, p. 408 - 411 (2007/10/02)
A novel enzyme, "Nα-benzyloxycarbonyl amino acid urethane hydrolase II", was isolated from the cell-free extract of Lactobacillus fermenti 36 ATCC 9338.The enzyme showed hydrolytic activity toward Nα-benzyloxycarbonyl arginine.The purified enzyme was homogenous as indicated by disc gel electrophoresis.The molecular weight of the native enzyme is about 200,000 as estimated by gel filtration method.The isoelectric point was 5.0.The enzyme activity was inhibited by p-chloromercuribenzoic acid and ethylenediaminetetraacetic acid.The presence of divalent cations (i.e., Co(2+) or Zn(2+)) is essential for its activity. Keywords - novel enzyme; Urathane Hydrolase II; hydrolytic enzyme; Z-Arg; Lactobacillus fermenti 36 ATCC 9338; characterization; purification
