70044-57-4

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 67-64-1 acetone 
• 1613-90-7 4-methoxy-N-[(E)-phenylmethylidene]aniline 
• 1468-95-7 9-hydroxymethylanthracene 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 1333320-89-0 ethyl 2-acetoxy-3-(4-methoxyphenylamino)-3-phenylacrylate 

Relevant academic research and scientific papers

Synthesis of a series of novel chiral Lewis base catalysts and their application in promoting asymmetric hydrosilylation of β-enamino esters

A series of novel chiral Lewis base catalysts were synthesized from l-serine and applied in the hydrosilylation of β-enamino esters, in which the optimal one promoted the reactions to afford a wide variety of β-amino esters in good yields with good enantioselectivities. It is noteworthy that several cyclic substrates were hydrosilylated under the optimal conditions to give the cyclic β-amino esters with high yields, good diastereoselectivities as well as good ee values. The Royal Society of Chemistry 2013.

A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral Bronsted acid-Rh2(OAc)4 Co-catalyzed enantioselective three-component reactions

A new approach to synthesize optically active β-amino-α-hydroxyl acid derivatives via chiral Bronsted acid-Rh2(OAc) 4 cocatalyzed three-component reactions of diazo acetates with alcohols and imines is reported. A matched reaction sy

Synthesis of 1,3-oxazolidines by copper-catalyzed addition of acetone and ethyl diazoacetate to imines

1,3-Oxazolidines are obtained in high yields by copper-catalyzed addition of ethyl diazoacetate to imines in the presence of acetone. Hydrolysis of the oxazolidines with 6N HCl yields 1,2-amino alcohols.