70045-30-6

Upstream product

• 88422-82-6 1-(3',4'-dimethoxybenzyl)-3,4-dihydroisoquinoline 
• 3230-65-7 3,4-dihydroisoquinoline 
• 108071-30-3 3,4-dimethoxyphenylmethylmagnesium chloride 
• 81763-89-5 Cyclohexyl-[1-(3,4-dihydro-1H-isoquinolin-2-yl)-meth-(Z)-ylidene]-amine 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 64-04-0 phenethylamine 
• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 
• 81763-81-7 Cyclohexyl-[1-[1-(3,4-dimethoxy-benzyl)-3,4-dihydro-1H-isoquinolin-2-yl]-meth-(E)-ylidene]-amine 
• 3972-81-4 N-(β-phenylethyl)-3,4-dimethoxyphenylacetamide 

Relevant academic research and scientific papers

NOVEL INDOLE AND PYRROLOPYRIDINE AMIDES

The present invention relates to indole and pyrrolopyridine amide derivatives of formula (I) wherein R1, R 2, R 3, U, V, W, X, Y, Z and ring A are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.

Inhibition of dopamine receptors by endogenous amines: Binding to striatal receptors and pharmacological effects on locomotor activity

Endogenous amine 1-benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ) derivatives are synthesized, and their activity for dopaminergic systems are evaluated in vitro and in vivo by receptor binding assay and pharmacological tests. It is proposed that 1BnTIQ d

S-tetrahydroprotoberberineoxidase, process for producing the same and use thereof

The invention relates to the enzyme S-tetrahydroprotoberberineoxidase, which oxidizes selectively S-tetrahydroprotoberberines and S-1-benzyl-1,2,3,4-tetrahydroisoquinoline in the presence of oxygen, resulting in the corresponding protoberberines and 1-ben

DIPOLE STABILIZED α-AMINO CARBANIONS. II. ALKYLATION OF TETRAHYDROISOQUINOLINES IN THE 1-POSITION.

N-Formamidine derivatives of tetrahydroisoquinolines are metalated and alkylated to give 1-substituted derivatives.Regeneration of the parent amine is accomplished by several different reagents.