70059-10-8Relevant academic research and scientific papers
A NEW SYNTHETIC APPROACH TO α,β-UNSATURATED PHOSPHONATES (1-METHYLENEALKANE-PHOSPHONATES)
Inokawa, S.,Yamamoto, H.
, p. 79 - 82 (2007/10/02)
α,β-Unsaturated phosphonates were prepared in good yields by refluxing 1,2-epoxy-1-alkyl-ethanephosphonates in methanol with thiourea (5 equiv.) for 4 hours.
New Synthesis and Hydroboration of Vinylphosphonates
Yamashita, Mitsuji,Kojima, Mitsumasa,Yoshida, Hiroshi,Ogata, Tsuyoshi,Inokawa, Saburo
, p. 1625 - 1628 (2007/10/02)
The Arbuzov reaction of trimethyl and triethyl phosphites with acyl chlorides gave 1-oxoalkylphosphonates in 57-80percent yields.The Wittig reaction of the phosphonates with methylenetriphenylphosphorane gave vinylphosphonates in 25-59percent yields.Hydroboration of vinylphosphonates in oxolane gave 2-hydroxyethylphosphonates in 50-65percent yields.The procedure seems to be a good synthetic method to afford 1-alkyl-substituted 2-hydroxyethylphosphonates which have one more carbon atom than the starting 1-oxoalkylphosphonates.
