700863-95-2

Basic information

• Product Name: 2,5-di-O-benzyl-D-manno-hexodialdose
• Synonyms: 2,5-di-O-benzyl-D-manno-hexodialdose
• CAS NO: 700863-95-2
• Molecular Weight: 358.391
• Mol File: 700863-95-2.mol

Chemical Properties

• CAS DataBase Reference: 2,5-di-O-benzyl-D-manno-hexodialdose(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-di-O-benzyl-D-manno-hexodialdose(700863-95-2)
• EPA Substance Registry System: 2,5-di-O-benzyl-D-manno-hexodialdose(700863-95-2)

Safety Data

• Hazardous Substances Data: 700863-95-2(Hazardous Substances Data)

Upstream product

• 227196-03-4 D-2,5-di-O-benzyl-chiro-inositol 
• 100-39-0 benzyl bromide 
• 110550-25-9 3,4-di-O-allyl-2,5-di-O-benzyl-D-chiro-inositol 
• 40617-60-5 1,2:5,6-bis-O-(1-methylethylidene)-D-chiro-inositol 
• 700863-94-1 3,4-di-O-allyl-D-chiro-inositol 
• 701272-07-3 3,4-di-O-allyl-1,2:5,6-di-O-isopropylidene-D-chiro-inositol 

Downstream Products

• 700863-96-3 N-benzyl-3,6-di-O-benzyl-D-manno-3,4,5,6-tetrahydroxyazepane 

Relevant articles and documents

Conformation inversion of an inositol derivative by use of silyl ethers: A modified route to 3,6-di-O-substituted-L-ido-tetrahydroxyazepane derivatives

The tans-diequatorial 3,4-diol of 2,5-di-O-benzyl-D-chiro-inositol cleaved selectively with the periodate ion in the presence of the trans-diaxial 1,6-diol to give a dialdehyde (dialdose) from which 3,6-di-O-benzyl-D- mannotetrahydroxyazepane (1) was made. The trans-diaxial 1,6-diol of 3,4-di-O-allyl-2,5-di-O-benzyl-D-chiro-inositol was not cleaved satisfactorily by periodate, but replacement of the allyl substituents with tert-butyldimethylsilyl groups caused conformational inversion of the inositol ring, and the resulting trans-diequatorial 1,6-diol cleaved efficiently to give a dialdehyde from which 3,6-di-O-benzyl-L-tdo-tetrahydroxyazepane (2) can be prepared.