70110-39-3Relevant academic research and scientific papers
Fe3O4@SiO2 nanoparticle supported ionic liquid for green synthesis of antibacterially active 1-carbamoyl-1-phenylureas in water
Nasrollahzadeh, Mahmoud,Issaabadi, Zahra,Sajadi, S. Mohammad
, p. 27631 - 27644 (2018/08/16)
In the present work, we have designed a novel, heterogeneous and recyclable magnetic Br?nsted acidic ionic liquid based on 5-phenyl-1H-tetrazole. The {Fe3O4@SiO2@CH2)35-phenyl-1H-tetrazole-SO3H/Cl} ([FSTet-SO3H]Cl) was prepared via the immobilization of 5-phenyl-1H-tetrazole-bonded sulfonic acid onto the surface of silica-coated magnetic nanoparticles using 3-chloropropyltriethoxysilane as a linker. The catalyst was characterized by XRD, TEM, FESEM, EDS, TG-DTA, and FT-IR. The ability and high activity of this catalyst were demonstrated in the synthesis of 1-carbamoyl-1-phenylureas with good to excellent yields via a new, simple and one-pot procedure in aqueous media under reflux conditions. This procedure has advantages such as high yields, short reaction times, a simple methodology and work-up process, green reaction conditions, high stability, catalytic activity, and easy preparation, separation and reusability of the catalyst. The synthesis of these compounds was confirmed by FT-IR, 1H NMR, 13C NMR and CHN. In addition, we investigated the biological properties of the 1-carbamoyl-1-phenylureas as newly synthesized compounds. The described catalyst could be easily separated from the reaction mixture by additional magnetic force and reused several times without a remarkable loss of its catalytic activity and any considerable changes in the product yield and the reaction time.
Synthesis, characterization and antibacterial activity of new 1,2- and 1,4-bis(n'-substituted thioureido)benzene derivatives
Saeed, Aamer,Abbas, Naeem,Ashraf, Zaman,Bolte, Michael
, p. 273 - 278 (2013/12/04)
Synthesis of two series of 1,2- and 1,4-bis(thioureido)benzene derivatives was accomplished by the treatment of corresponding alkanoyl/aroyl chlorides with potassium thiocyanate in dry acetone to afford the respective isothiocyanates as intermediates. The
An efficient, facial and green synthesis of substituted thiourea
Pourshamsian, Khalil,Montazeri, Naser,Khameneh, Aylar Shams
experimental part, p. 837 - 839 (2012/08/07)
A series of novel substituted N,N'-di(arylaminothiocarbonyl)terephthalamide and 1,4-di(aryloylthioureido)benzene were synthesized by the reaction of terephthaloyl dichloride, ammonium thiocyanate and primary amines, 1,4-phenylenediamine and acyl halide derivatives. The reaction has been completed within 0.5 h in solvent-free condition by grinding the mixture of reactants and afforded the substituted thiourea in good yields.
Phase transfer catalyzed synthesis of arene-bis-aroyl thiourea derivatives
Zhang,Wei,Gao
, p. 700 - 702 (2007/10/03)
Reaction of arene diamines with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase transfer catalysis using polyethylene-glycol-600 (PEG-600) as the catalyst furnishes arene-bis-aroyl thioureas 3a-I in good to excellent yiel
