70119-96-9Relevant academic research and scientific papers
Intermediates for making 1-(3-benzyloxyphenyl)-1,1-dimethylheptane
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, (2008/06/13)
Process for making 1-(3-benzyloxyphenyl)-1,1-dimethylheptane, a valuable intermediate for the preparation of analgesic agents, which comprises benzylation of 3-hydroxyacetophenone to produce 3-benzyloxyacetophenone which is converted to 1-(3-benzyloxyphenyl)-1-methylheptan-1-ol via Grignard reaction with n-hexylmagnesium bromide; chlorination of said heptanol by reaction with hydrogen chloride followed by methylation of the thus-produced 1-(3-benzyloxyphenyl)-1-chloro-1-methylheptane with trimethylaluminum.
Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives
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, (2008/06/13)
Compounds useful for pharmacological and medicinal purposes having the formulae STR1 wherein R is H, C1 -C5 alkanoyl; R1 is H, benzyl, C1 -C5 alkanoyl, P(O)(OH)2, --CO(CH2)2
