701300-00-7

Basic information

• Product Name: 1-benzyl-N-[(1-trityl-1H-imidazol-4-yl)methyl]piperidin-4-amine
• Synonyms: 1-benzyl-N-[(1-trityl-1H-imidazol-4-yl)methyl]piperidin-4-amine
• CAS NO: 701300-00-7
• Molecular Weight: 512.698
• Mol File: 701300-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-N-[(1-trityl-1H-imidazol-4-yl)methyl]piperidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-N-[(1-trityl-1H-imidazol-4-yl)methyl]piperidin-4-amine(701300-00-7)
• EPA Substance Registry System: 1-benzyl-N-[(1-trityl-1H-imidazol-4-yl)methyl]piperidin-4-amine(701300-00-7)

Safety Data

• Hazardous Substances Data: 701300-00-7(Hazardous Substances Data)

Upstream product

• 50541-93-0 4-amino-1-benzylpiperidine 
• 33016-47-6 (1-tritylimidazol-4-yl)carboxaldehyde 

Downstream Products

• 701300-01-8 tert-butyl (1-benzylpiperidin-4-yl)[(1-trityl-1H-imidazol-4-yl)methyl]carbamate 

Relevant articles and documents

Synthesis and biological evaluation of the metabolites of 2-(1-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propanoyl}piperidin-4-yl)-5-methyl-1,2-dihydro-3H-imidazo[1,5-c]imidazol-3-one

We have recently discovered imidazo[1,5-c]imidazol-3-one derivative 1 as a potent, selective, and orally bioavailable factor Xa (FXa) inhibitor. In this study, we have synthesized metabolites of 1 and evaluated their biological activities. As a result, we identified the active metabolites S-5 and 6 with a potent FXa inhibitory activity comparable to 1 and a favorable pharmacokinetic profile in monkeys.