70147-48-7Relevant articles and documents
MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS
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, (2014/09/29)
The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula I: The invention also provides processes for making the compounds described herein. Furthermore, the present invention p
Doubly carbon-branched pentoses: synthesis of both enantiomers of 2,4-di-C-methyl arabinose and 2-deoxy-2,4-di-C-methyl arabinose using only acetonide protection
Victoria Booth,Jenkinson, Sarah F.,Best, Daniel,Nieto, Fernando Fernández,Estévez, Ramón J.,Wormald, Mark R.,Weymouth-Wilson, Alexander C.,Fleet, George W.J.
scheme or table, p. 5088 - 5093 (2009/12/01)
An acetonide is the only protecting group used in the synthesis of both the enantiomers of 2,4-di-C-methyl arabinose and 2-deoxy-2,4-di-C-methyl arabinose via the enantiomeric 3-C-methyl-l-erythronolactone [from 2-C-methyl-d-ribono-lactone or d-ribose] and 3-C-methyl-d-erythronolactone [from d-tagatose or l-ribose]. NMR studies on unprotected C-methyl arabinoses show that methyl branching significantly affects the ratios of pyranose and furanose forms present in aqueous solution.