70152-27-1 Usage
General Description
1-benzyl-4-(3-phenylpropyl)-1,2,3,6-tetrahydropyridine, also known as MPTP, is a chemical compound that has been used in research to induce Parkinson's disease-like symptoms in animals. It is a neurotoxin that selectively damages the dopaminergic neurons in the brain, leading to symptoms such as tremors, muscle rigidity, and bradykinesia. MPTP is converted into a toxic metabolite, MPP+, by the enzyme MAO-B, which then accumulates in the brain and causes damage to the dopamine-producing neurons. The use of MPTP in research has been instrumental in understanding the underlying mechanisms of Parkinson's disease and in developing potential treatments for the condition.
Check Digit Verification of cas no
The CAS Registry Mumber 70152-27-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,1,5 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70152-27:
(7*7)+(6*0)+(5*1)+(4*5)+(3*2)+(2*2)+(1*7)=91
91 % 10 = 1
So 70152-27-1 is a valid CAS Registry Number.
70152-27-1Relevant articles and documents
3-thienyl and 3-furanyl pyrrolidine modulators of chemokine receptor activity
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, (2008/06/13)
The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4c, R4d, and R4fare defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.
