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4-Methylbicyclo[2.2.2]octane-1-carboxylic acid is a chemical compound with the molecular formula C10H16O2. It is a white crystalline solid that is soluble in organic solvents. 4-Methylbicyclo[2.2.2]octane-1-carboxylic acid is a derivative of bicyclo[2.2.2]octane, a bicyclic hydrocarbon, with a methyl group attached to the 4-position and a carboxylic acid group at the 1-position. It is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of certain insecticides and antifungal agents. The compound is known for its stability and can be synthesized through various chemical reactions, such as the cyclization of appropriate precursors. Its unique structure and properties make it a valuable building block in organic chemistry.

702-67-0

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702-67-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 702-67-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 702-67:
(5*7)+(4*0)+(3*2)+(2*6)+(1*7)=60
60 % 10 = 0
So 702-67-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H16O2/c1-9-2-5-10(6-3-9,7-4-9)8(11)12/h2-7H2,1H3,(H,11,12)

702-67-0Relevant academic research and scientific papers

Transmission of Polar Substituent Effects Through the Bicyclooctane Ring System as Monitored by NMR Shifts: a 13C NMR Study of 4-Substituted-1-methylbicyclooctanes

Adcock, William,Abeywickrema, Anil N.,Iyer, V. Sankar,Kok, Gaik B.

, p. 213 - 220 (2007/10/02)

Carbon-13 substituent chemical shifts (SCS) are reported for the methyl group of a series of 4-substituted 1-methylbicyclooctanes covering a wide range of electronic substituent effects.Unlike the 13C SCS of the α-carbon centre in various unsaturat

Polar Substituent Effects on 19F Chemical Shifts of Aryl and Vinyl Fluorides: A Fluorine-19 Nuclear Magnetic Resonance Study of Some 1,1-Difluoro-2-(4-substituted-bicyclooct-1-yl)ethenes

Adcock, William,Kok, Gaik B.

, p. 1079 - 1087 (2007/10/02)

An extensive series of 1,1-difluoro-2-(4-substituted-bicyclooct-1-yl)ethenes (2) covering a diverse range of substituents ( X = H, NO2, CN, CF3, COOCH3, F, Cl, Br, OCH3, C6H5, C2H, C2Si(CH3)3, CH3, and C(CH3)3) have been synthesized and their 19F N

LIQUID CRYSTAL PROPERTIES OF 4-n-ALKYL- AND 4-n-ALKOXY-PHENYL 4-n-ALKYLBICYCLO(2. 2. 2)OCTANE-1-CARBOXYLATES.

Gray,Kelly

, p. 95 - 108 (2007/10/02)

Two new series of esters incorporating the 1,4-disubstituted bicyclo(2. 2. 2)octane ring system are reported. Thirty-three 4-n-alkylphenyl 4-n-alkylbicyclo(2. 2. 2)octane-1-carboxylates and thirty 4-n-alkoxyphenyl 4-n-alkylbicyclo(2. 2. 2)octane-1-carboxylates have been prepared and found to exhibit wide-range nematic phases persisting until higher temperatures than those of the corresponding esters containing either the trans-1,4-disubstituted cyclohexane ring or the 1,4-disubstituted benzene ring in place of the bicyclo-octane ring. Mixtures of these novel bicyclo-octane esters with cyanobiphenyls have been found to be superior for multiplexing applications in twisted nematic cells to equivalent mixtures employing 4-n-alkylphenyl 4-n-alkoxybenzoates or 4-n-alkoxyphenyl trans-4-n-alkylcyclohexane-1-carboxylates.

THIAZOLE CARDIOVASCULAR AGENTS

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, (2008/06/13)

1-Alkylamino-3-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxy)-2-propan ol;5-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxymethylene-N-alkyloxazol idin e and/or 2-substituted oxazolidine derivatives thereof, and methods of making such compounds. The compounds exhibit cardiovascular activity and are useful in the treatment of abnormal heart conditions in mammals. The compounds are also useful in the treatment of hypertension in mammals. The 5-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxymethylene)-N-alkyloxazolid ines and derivatives are also intermediates for the 1-alkylamino-3-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxy)-2-propanols . The 1-alkylamino-3-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxy)-2-propanols can be prepared by base or acid hydrolysis of the corresponding 5-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxymethylene)-N-alkyloxazolid ine or derivative; or by treatment of the corresponding 3-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxy)-2,3-epoxypropane with the desired alkylamine. Similarly the 5-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxymethylene)-N-alkyloxazolid ine or derivative can be prepared from the corresponding 1-alkylamino-3-(5-carbocyclicalkylaminocarbonylthiazol-2-yloxy)-2-propanols via treatment with an aldehyde or ketone.

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