70200-36-1

Upstream product

• 70224-28-1 (R)-(-)-3-methyl-1-pentanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 616-16-0 (R)-2-Methyl-1-butanol 
• 16958-25-1 (R)-3-methylpentanoic acid 
• 63473-60-9 (R)-3-methylpentanedioic acid monomethyl ester 
• 32365-96-1 methyl 3-(R)-methyl-5-hydroxypentanoate 
• 70200-35-0 (S)-4-formyl-3-methylbutyl acetate 
• 70200-33-8 (R)-3,7-dimethyl-7-hydroxy-5-octenyl acetate 
• 96924-79-7 methyl (R)-5-mesyloxy-3-methylpentanoate 
• 250229-60-8 (R)-3-methylpentanenitrile 
• 46481-05-4 (R)-2-methyl-1-butanol 4-methylbenzenesulfonate 

Downstream Products

• 70224-30-5 (R,Z)-14-methylhexadec-8-en-1-one 
• 250229-74-4 (2R,6R,10R)-1-tert-butyldiphenylsilyloxy-2,6,10-trimethyldodecane 

Relevant academic research and scientific papers

Pheromone synthesis, CXCVIII. Synthesis of (1S,2S,6S,10R)- and (1S,2R,6R,10R)-1,2,6,10-tetramethyldodecyl propanoate, the components of the sex pheromone of the pine sawfly, Microdiprion pallipes

(1S,2S,6S,10R)- and (1S,2R,6R,10R)-1,2,6,10-tetramethyldodecyl propanoate (1 and 2), the components of the pheromone of Microdiprion pallipes, were synthesized from two chiral and nonracemic building blocks, (R)-3-tert-butoxycarbonyl-2-methylpropanoic acid (D) and (2R,6S)-7-acetoxy- 2,6-dimethyl-1-heptanol (G), by employing lipase-catalyzed kinetic resolution in a later step.

Synthesis of Chiral Alcohol and Ester Pheromones through Enzyme-Catalysed Hydrolysis using Pseudomonas fluorescens Lipase: Preparation of (2R,6S,10S)-6,10,14-Trimethylpentadecan-2-ol and the Propionate of (2R,8R)-8-Methyldecan-2-ol

(2R,6S,10S)-6,10,14-Trimethylpentadecan-2-ol , one of the stereoisomers of the sex pheromone of Corcyra cephalonica Stainton, was synthesized in highly optically pure form by the hydrolysis of the 2,2,2-trichloroethyl carbonate of (2RS,6S,

SYNTHESIS OF THE PROPIONATES OF (2R,8R)- AND (2RS,8R)-8-METHYL-2-DECANOL, THE ATTRACTANTS OF THE WESTERN CORN ROOTWORM

The propionate of (2R,8R)-8-methyl-2-decanol, (2R,8R)-1, an attractant of the western corn rootworm, Diabrotica virgifera Le Conte, has been prepared by a synthetic route in which enantiomerically pure methyl hydrogen (R)-3-methylglutarate, (R)-2, and (S)-glutamic acid, (S)-3, have been used as chiral precursors.In this convergent synthesis, (R)-2 and (S)-3 have been stereospecifically converted into (R)-1-bromo-3-methylpentane, (R)-4, and (R)-1,4-pentanediol, (R)-5, respectively.An analogous synthetic scheme has been followed to prepare biologically active (2RS, 8R)-1 starting from (R)-4 and racemic 5.

SYNTHESIS OF THE PROPIONATES OF (2R,8R)- AND (2S,8R)-8-METHYL-2-DECANOL, THE PHEROMONE OF THE WESTERN CORN ROOTWORM, EMPLOYING CHIRAL COMPOUNDS OF MICROBIAL ORIGIN AS STARTING MATERIALS

The attractants of the western corn rootworm (Diabrotica virgifera virgifera Le Conte), the propionates of (2R,8R)- and (2S,8R)-8-methyl-2-decanol, were synthesized from (R)-(+)-citronellol and the enantiomers of ethyl β-hydroxybutyrate of microbial origin.