70219-83-9Relevant academic research and scientific papers
Sulfonium salts as prenyl, geranyl, and isolavandulyl transfer agents towards benzoylphloroglucinol derivatives
Brajeul, Solenn,Delpech, Bernard,Marazano, Christian
, p. 5597 - 5600 (2008/03/11)
In search for new methods aiming biomimetic synthesis of polyprenylated acylphloroglucinols (PPAPs), we now report the results of an evaluation of sulfonium salts as prenyl, geranyl, and isolavandulyl transfer agents towards benzoylphloroglucinol derivatives, in neutral conditions. As a result, conditions were found for rather efficient C-prenylation of these compounds. The corresponding trimethyl ether gave the best results, but the reaction was accompanied by a deacylation process. Geranyl transfer was also observed, but in low yield, and, interestingly, an isolavandulyl group could be introduced with an appreciable yield.
Synthesis of Vismiaphenone-B: A Naturally Occurring Prenylated Benzophenone
Pathak, V. P.,Khanna, R. N.
, p. 253 - 254 (2007/10/02)
Vismiaphenone-B, 5-C-prenyl-2,6-dihydroxy-6'',6''-dimethylchromenobenzophenone (II), has been synthesised starting from 2,4,6-trihydroxybenzophenone (V).V on prenylation with prenyl bromide in the presence of methanolic sodium methoxide yields three products, viz. 3,5-di-C-prenyl-2,4,6-trihydroxybenzophenone (VI), 2,6-dihydroxy-4-O-prenylbenzophenone (VII) and a brown oil, which could not be characterised.VI on cyclodehydrogenation with DDQ affords II, identical in all respects (UV, IR and PMR) with a natural sample.
Synthesis of Naturally Occurring Prenylated Benzophenones. Vismiaphenone A, Vismiaphenone B, and Isovismiaphenone B
Pathak, Ved Prakash,Khanna, Rajinder Nath
, p. 2264 - 2266 (2007/10/02)
2,4,6-Trihydroxybenzophenone on prenylation with 2-methyl-3-buten-2-ol in the presence of (C2H5)2O*BF3 yielded 2,4,6-trihydroxy-3,5-diprenylbenzophenone (3), 2,6-dihydroxy-4-prenyloxybenzophenone, 2,6-dihydroxy-3-prenyl-4-prenyloxybenzophenone, a benzodip
