7023-79-2

Usage

Uses

Used in Organic Synthesis:
Ethanone, 1-(3-bromophenyl)-2-diazois used as a diazo transfer reagent in organic synthesis for the purpose of introducing the diazo group into other molecules. This functionalization and modification process is crucial for the development of new compounds with specific properties and applications.
Used in Chemical Research:
In the field of chemical research, Ethanone, 1-(3-bromophenyl)-2-diazois utilized to study the reactivity and properties of diazo compounds. Its unique structure allows researchers to explore various reaction pathways and mechanisms, contributing to the advancement of chemical knowledge and the discovery of novel synthetic methods.
Used in Pharmaceutical Industry:
Ethanone, 1-(3-bromophenyl)-2-diazomay be used in the pharmaceutical industry as a key intermediate in the synthesis of pharmaceutical compounds. Its reactivity and ability to introduce the diazo group can be leveraged to create new drug candidates with potential therapeutic applications.
Used in Material Science:
In material science, Ethanone, 1-(3-bromophenyl)-2-diazocan be employed in the development of novel materials with specific properties. The introduction of the diazo group can alter the physical and chemical characteristics of materials, leading to the creation of new materials with improved performance in various applications.
It is important to handle Ethanone, 1-(3-bromophenyl)-2-diazowith caution, as diazo compounds are known for their explosive properties and must be managed carefully in a controlled laboratory setting to ensure safety.

Upstream product

• 3387-25-5 1,3-bis(3-bromophenyl)-1,3-propanedione 
• 1711-09-7 3-bromobenzoyl chloride 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 585-76-2 m-bromobenzoic acid 
• 186581-53-3 diazomethane 
• 106134-16-1 3'-bromo-2,2-dihydroxy-acetophenone 

Downstream Products

• 1878-67-7 3-Bromophenylacetic acid 
• 199942-81-9 2-{2-[3-(3-bromophenyl)-7-chloro-6-(3-cyclopropyl-ureido)-2-oxo-1,2-dihydroquinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 199942-79-5 2-{2-[3-(3-bromophenyl)-7-chloro-6-nitro-2-oxo-1,2-dihydroquinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 199942-80-8 2-{2-[6-amino-3-(3-bromophenyl)-7-chloro-2-oxo-1,2-dihydroquinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 199942-77-3 2-[2-(3-bromophenyl)-acetylamino]-4-chloro-5-nitrobenzoic acid methyl ester 
• 199942-78-4 3-(3-bromophenyl)-7-chloro-4-hydroxy-6-nitro-1H-quinolin-2-one 
• 98288-51-8 2-(3-bromophenyl)acetyl chloride 
• 74048-09-2 2-methyl-5-(m-bromophenyl)oxazole 
• 1391739-30-2 1-(3-bromophenyl)-2-morpholinoethane-1,2-dione 

Relevant academic research and scientific papers

Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360

Starting from lead compound 4, the 1,4-oxazine headgroup was optimized to improve potency and brain penetration. Focusing at the 6-position of the 5-amino-1,4-oxazine, the insertion of a Me and a CF3 group delivered an excellent pharmacological profile wi

Tandem Synthesis of α-Diazoketones from 1,3-Diketones

A highly efficient synthesis of α-diazoketone was achieved by simply stirring the mixture of 1,3-diketone, TsN3, and MeNH2 in EtOH. It was a tandem reaction including a novel primary amine-catalyzed Regitz diazo transfer of 1,3-diket

One-pot synthesis of polyfunctional pyrazoles: An easy access to α-diazoketones from arylglyoxal monohydrates and tosylhydrazine

A new and efficient method for the generation of α-diazoketones has been developed from arylglyoxal monohydrates and tosylhydrazine at room temperature. 1,3-Dipolar cycloaddition reactions were used to constructing polyfunctional pyrazole derivatives by the reaction of generated α-diazoketones in situ with electron-deficient alkenes, quinones and coumarins in one pot. The one-dimensional molecular packing of 1H-benzo[f]indazole-4,9-dione derivatives along the c direction demonstrated a helical chain formation via N-H?O hydrogen-bonding.

Quinolones as gonadotropin releasing hormone (GnRH) antagonists: Simultaneous optimization of the C(3)-aryl and C(6)-substituents

A series of 3-arylquinolones was prepared and evaluated for their ability to act as gonadotropin releasing hormone (GnRH) antagonists. A variety of substitution patterns of the 3-aryl substituent are described. The 3,4,5-trimethylphenyl substituent (23h) was found to be optimal. (C) 2000 Elsevier Science Ltd. All rights reserved.