7025-16-3

Upstream product

• 3529-82-6 3-nitrophenyl isothiocyanate 
• 99-09-2 3-nitro-aniline 
• 72757-95-0 (3-nitro-phenyl)-dithiocarbamic acid; ammonium salt 
• 79925-03-4 4‐(3‐nitrophenyl)thiosemicarbazide 

Downstream Products

• 1618101-37-3 C₈H₇N₅O₂S 
• 133088-48-9 5-methylsulfonyl-1-(3-nitrophenyl)-1H-tetrazole 
• 1618101-45-3 5-[(3,5-dinitrobenzyl)oxy]-1-(3-nitrophenyl)-1H-tetrazole 
• 1618101-04-4 5-[(3,5-dinitrobenzyl)sulfanyl]-1-(3-nitrophenyl)-1H-tetrazole 
• 1618101-07-7 5-[(2,4-dinitrobenzyl)sulfanyl]-1-(3-nitrophenyl)-1H-tetrazole 

Relevant academic research and scientific papers

4-(5-tetrazole sulfydryl hexyloxy) 3-phenylcoumarin robustic acid type fluorescent probes and preparation method thereof

The invention discloses six 4-(5-tetrazole sulfydryl hexyloxy) 3-phenylcoumarin robustic acid type fluorescent probes as well as a preparation method and application thereof. The general structural formula of the fluorescent probes is shown in the specification. The fluorescent probes combine the fluorescence characteristics of coumarins and tetrazole derivatives. The probes show very high selectivity and sensitivity to lead ions in a DMSO/H2O solution, have obvious hyperchromic effect compared with other ions, have changed maximum absorption peaks, and can be used as lead ion fluorescent probes.

Several 4-(5-tetrazole mercaptopropoxy) glycyrrhiza uralensis A-type fluorescent probes and preparation method thereof

The invention discloses six 4-(5-tetrazole sulfydryl propoxy)glycyrrhiza uralensis A type fluorescent probes with different substituent groups as well as a preparation method and an application of thefluorescent probes. According to the present invention, the glycyrrhiza glabra A-1, 2, 3, 4-tetrazole-thiol type fluorescent probe combines the excellent fluorescence characteristics of coumarins andtetrazole derivatives, provides high selectivity and high sensitivity for lead ions in a DMSO/H2O solution, provides the significant hyperchromic effect, and can achieve the purpose of trace detection of lead ions.

Modified julia-kocienski reaction promoted by means of m-NPT (nitro-phenyltetrazole) sulfone

m-Nitrophenyltetrazole sulfone (2) was employed in the Julia-Kocienski reaction. The olefination reaction between 2 and carbonyl compounds proceeded smoothly under Masamune-Roush conditions (DBU and LiCl). These conditions were also applicable to our catechin derivative synthesis. Furthermore, phenolic mesylate was also tolerated in this mild reaction.