70276-70-9

Upstream product

• 40024-22-4 N-<2,2,2-Trifluor-1-(trifluormethyl)ethyliden>-p-toluamid 
• 40023-97-0 5-(p-Tolyl)-2,2,2-trimethoxy-3,3-bis(trifluormethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-en 
• 140-88-5 ethyl acrylate 
• 54289-96-2 N-<1-(Chlordifluormethyl)-2,2-difluorvinyl>-4-methylbenzimidoylchlorid 
• 78786-66-0 4-(Difluormethylen)-5,5-difluor-2-(p-tolyl)-Δ²-oxazolin 
• 52786-59-1 N-<2-Chlor-1-(chlordifluormethyl)-2,2-difluorethyliden>-p-toluamid 

Downstream Products

• 70276-77-6 2-(p-Tolyl)-4-(trifluormethyl)oxazol 
• 128538-56-7 5-Azido-2-p-tolyl-4-trifluoromethyl-oxazole 
• 70276-68-5 5-Diethylamino-2-(p-tolyl)-4-(trifluormethyl)oxazol 
• 128538-60-3 C₂₉H₂₂F₃N₄OP 
• 128538-64-7 C₂₉H₂₂F₃N₂OP 
• 128538-68-1 N-[1-Cyano-2,2,2-trifluoro-eth-(E)-ylidene]-4-methyl-benzamide 

Relevant academic research and scientific papers

Cycloreversion Mechanism of 3,3-Bis(trifluoromethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-enes

2,2,2-Trimethoxy-3,3-bis(trifluoromethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-enes on thermolysis undergo a 1,3-dipolar cycloreversion reaction with formation of bis(trifluoromethyl) substituted nitrile ylides.Trapping reactions of the 1,3-dipolar species with α,β-unsaturated carboxylic acid esters and nitriles are described. 2-Aryl-3-carbethoxy-5,5-bis(trifluoromethyl)-1-pyrrolines obtained undergo an uncatalyzed autoxidation process to give 2-aryl-3-carbethoxy-3-hydroxy-5,5-bis(trifluoromethyl)-1-pyrrolines. 5,5-Difluoro-4-trifluoromethyl-2-oxazolines and 5-fluoro-4-tri fluoromethyl-oxazoles formed as by-products indicate that the thermal induced -cycloreversion reaction of 2,2,2-trimethoxy-3,3-bis(trifluoromethyl)-2,2-dihydro-1,4,2-oxazaphosphol-4-enes is most likely a stepwise process. - Keywords: -Cycloreversion Reactions, Trifluoromethyl Substituted 1,3-Dipoles, -Cycloaddition Reactions, 5,5-Difluoro-4-trifluoromethyl-2-oxazolines, 5-Fluoro-4-trifluoromethyl-oxazoles

Reaction Behaviour of Trifluoromethyl Groups. Synthesis of 1,3-Azoles from Trifluoromethyl-substituted Hetero-1,3-dienes

4,4-Bis(trifluoromethyl)-substituted 1-oxa-3-aza-1,3-butadienes 1, 1-thia-3-aza-1,3-butadienes 2 as well as 1,3-diaza-1,3-butadienes 3 on heating with tin(II) chloride yield 5-fluoro-4-trifluoromethyl-substituted oxazoles 4, thiazoles 5, and imidazoles 6,

SELEKTIVE EINFUEHRUNG VON FLUOR UND TRIFLUORMETHYLGRUPPEN IN HETEROCYCLISCHE SYSTEME SYNTHESE VON 5-FLUOR-4-TRIFLUORMETHYL-OXAZOLEN

N--imidoylchlorides 4 on heating with trimethyl phosphate yield 5,5-difluoro-4-difluoromethylen-2-oxazolines 5.In the presence of caesium fluoride the latter rearrange to give 5-fluoro-4-trifluoromethyl-oxazoles