7028-67-3

Basic information

• Product Name: 3-(4-METHYLTHIOBENZOYL)PROPIONIC ACID
• Synonyms: 3-(4-METHYLTHIOBENZOYL)PROPIONIC ACID;4-[4-(METHYLTHIO)PHENYL]-4-OXOBUTANOIC ACID;4-OXO-4-(4-THIOMETHYLPHENYL)BUTYRIC ACID;3-(4-Methylthiobezoyl)propionic acid
• CAS NO: 7028-67-3
• Molecular Formula: C₁₁H₁₂O₃S
• Molecular Weight: 224.28
• Mol File: 7028-67-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 151-155°C
• Boiling Point: 442.4 °C at 760 mmHg
• Flash Point: 221.4 °C
• Appearance: /
• Density: 1.26 g/cm³
• Vapor Pressure: 1.32E-08mmHg at 25°C
• CAS DataBase Reference: 3-(4-METHYLTHIOBENZOYL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHYLTHIOBENZOYL)PROPIONIC ACID(7028-67-3)
• EPA Substance Registry System: 3-(4-METHYLTHIOBENZOYL)PROPIONIC ACID(7028-67-3)

Safety Data

• Hazardous Substances Data: 7028-67-3(Hazardous Substances Data)

Usage

General Description

3-(4-Methylthiobenzoyl)propionic acid is a chemical compound that belongs to the class of thioesters. It contains a propionic acid group as well as a 4-methylthiobenzoyl group. 3-(4-METHYLTHIOBENZOYL)PROPIONIC ACID is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the production of fragrances and flavoring agents. Additionally, 3-(4-Methylthiobenzoyl)propionic acid has potential applications in the development of new materials and in the study of organic chemistry.

InChI:InChI=1/C11H12O3S/c1-15-9-4-2-8(3-5-9)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14)/p-1

Upstream product

• 108-30-5 succinic acid anhydride 
• 100-68-5 methyl-phenyl-thioether 

Downstream Products

• 116174-33-5 4-(4-methylsulfanyl-phenyl)butyric acid 
• 675609-11-7 (S)-N-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]-4-oxo-4-(4-thiomethyl)phenylbutanamide 
• 692728-84-0 4-(4-chloro-benzyl)-7-methylsulfanyl-3,4-dihydro-2H-naphthalen-1-one 

Relevant articles and documents

Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3

Naphthalenic analogs of MCA-NAT (5-methoxycarbonylamino-N-acetyltryptamine) have been synthesized and evaluated as melatonin receptor ligands. Introduction of a methoxycarbonylamino substituent at the C-7 position of the naphthalenic nucleus yields MTsub

OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS

Novel compounds belonging to the class of oxazolidinones possessing potent antimycobacterial properties especially useful in the treatment of acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai. The compound and its pharmaceutically acceptable salts thereof act as antibacterial agents. Also disclosed is a method for inhibiting growth of mycobacterial cells a well as a method of treating mycobacterial conditions such as Mycobacterium tuberculoses, drug resistant Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai, comprising administering an antimycobacterially effective amount of the said compound and/or pharmaceutically acceptable salts thereof. There is also disclosed a process for the manufacture of the said compound or its pharmaceutically acceptable salts.