7029-05-2Relevant academic research and scientific papers
Metal coordination compound, intermediate, preparation method and applications thereof
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Paragraph 0411-0417, (2020/05/01)
The invention discloses a metal coordination compound, an intermediate, a preparation method and applications thereof. According to the invention, the metal coordination compound represented by a formula I can be used as a catalyst for an asymmetric catalytic hydrogenation reaction to efficiently and catalytically synthesize a series of chiral beta-aryl amides with high optical purity (ee value ofmore than 99%) particularly to asymmetrically and catalytically hydrogenate a tetra-substituted alkenyl amide compound to synthesize a chiral amide with high optical purity (ee value of more than 60%), wherein the ligand bearing capacity (s/c) can reach 100000.
Metal complex as well as preparation method, application and intermediate thereof
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Paragraph 0233-0239, (2017/12/30)
The invention discloses a metal complex as well as a preparation method, application and an intermediate thereof. A chiral diphosphine ligand or a metal complex thereof is adopted as a catalyst for an asymmetric hydrogenation reaction of pure alkyl tetra-substituted cyclic alkene amide, synthesis of a chiral cyclic amino compounds is achieved, and the chiral diphosphine ligand or the metal complex thereof is high in catalysis efficiency in the asymmetric hydrogenation reaction, high in product chiral purity and large in substrate application range.
