70290-83-4Relevant articles and documents
THE DEPENDENCE OF ASYMMETRIC INDUCTION ON SOLVENT POLARITY AND TEMPERATURE IN PEPTIDE SYNTHESIS
Benoiton, N. Leo,Kuroda, K.,Chen, F. M. F.
, p. 3361 - 3364 (2007/10/02)
When a racemic 2,4-dialkyl-5(4H)-oxazolone reacts with an L-amino acid ester, the D-L epimer is formed in excess in apolar solvents and the L-L epimer is formed in excess in polar solvents, the proportion of L-L isomer increasing with decreasing temperature.