70291-89-3

Upstream product

• 51-21-8 5-fluorouracil 
• 645-96-5 Benzeneselenol 
• 1820-81-1 5-chlorouracil 
• 1666-13-3 diphenyl diselenide 
• 66-22-8 uracil 
• 696-07-1 5-iodouracil 

Relevant academic research and scientific papers

Phenylselenenyl- and Phenylthio-Substituted Pyrimidines as Inhibitors of Dihydrouracil Dehydrogenase and Uridine Phosphorylase

Lithiation of 5-bromo-2,4-bis(benzyloxy)pyrimidine (3) with n-BuLi at -80 deg C followed by the addition of diphenyl diselenide or diphenyl disulfide as an electrophile furnished the corresponding 5-(phenylhetera)-2,4-bis(benzyloxy)pyrimidine, which on ex

Practical and sustainable approach for clean preparation of 5-organylselanyl uracils

An eco-friendly, sustainable and practical method for the efficient preparation of 5-organylselanyl uracils through the electrochemical selenylation of uracils and diorganyl diselenides at room temperature under oxidant- and external electrolyte-free cond

Electrochemical Synthesis of 5-Selenouracil Derivatives by Selenylation of Uracils

A simple and efficient electrochemical selenylation of uracils in the presence of NH4I for the synthesis of 5-selenouracils has been developed. This transformation was performed in the transition metal-free, oxidant-free, and aerobic conditions, providing a rapid and practical protocol to 5-selenouracil derivatives.

Method for preparing 5-sulfur/selenium-modified uracil derivative

The invention belongs to the field of organic chemistry and particularly relates to a method for efficiently preparing a 5-sulfur/selenium-modified uracil derivative. The method comprises the steps ofenabling a thiophenol compound shown as a formula I or

A NaI/H2O2-Mediated Sulfenylation and Selenylation of Unprotected Uracil and Its Derivatives

An efficient iodide-catalyzed/hydrogen peroxide mediated sulfenylation and selenylation of unprotected uracil and its derivatives with simple thiols and diselenides was established. This coupling tolerates a broad variety of functional groups to provide d

Synthesis of substituted uracils by the reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles under focused microwave irradiation

Under microwave irradiation, the nucleophilic substitution reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles was complete within several minutes with yields up to 99%. The method using microwave irradiation is superior to th

Efficient phenylsulfenylation and phenylselenenylation at the 5-position of uracil nucleosides with disulfide and diselenide mediated by [bis(trifluoroacetoxy)iodo] benzene

A series of uracil nucleosides reacted with diphenyl disulfide or diphenyl diselenide in the presence of hypervalent iodine reagent, [bis(trifluoroacetoxy)iodo]benzene, in acetonitrile to give the corresponding C-5 phenylsulfenylated or phenylselenenylate