703-63-9 Usage
Uses
Used in Chemical Research:
2,4-Dimethylquinazoline is used as a research compound for its unique structural properties, which make it valuable in the study of chemical reactions and synthesis processes. Its low solubility in water also provides a unique challenge for researchers to explore its behavior in different solvents and conditions.
Used in Synthesis Processes:
2,4-Dimethylquinazoline is used as a building block or intermediate in the synthesis of more complex organic compounds. Its specific structure allows for the creation of a variety of derivatives, which can be further used in pharmaceutical, material science, or other chemical applications.
Used in Laboratory Settings:
2,4-Dimethylquinazoline is used as a reference compound in laboratory experiments, where its properties can be compared to other similar compounds. This helps researchers understand the effects of structural variations on the behavior of these compounds in different chemical environments.
Check Digit Verification of cas no
The CAS Registry Mumber 703-63-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 703-63:
(5*7)+(4*0)+(3*3)+(2*6)+(1*3)=59
59 % 10 = 9
So 703-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2/c1-7-9-5-3-4-6-10(9)12-8(2)11-7/h3-6H,1-2H3
703-63-9Relevant academic research and scientific papers
Microwave-promoted syntheses of quinazolines and dihydroquinazolines from 2-aminoarylalkanone O-phenyl oximes
Portela-Cubillo, Fernando,Scott, Jackie S.,Walton, John C.
supporting information; experimental part, p. 4934 - 4942 (2009/12/01)
(Chemical Equation Presented) A wide range of biologically active compounds contain the quinazoline ring system. A new free-radical-based method of making functionalized quinazolines is described, which relies on microwave-promoted reactions of O-phenyl oximes with aldehydes. A small set of 2-aminoaryl alkanone O-phenyl oximes was prepared and shown to produce dihydroquinazolines when mixed with an aldehyde in toluene and subjected to microwave heating. When ZnCl2 was included in the reaction mixture, fully aromatic quinazolines were produced in high yields by a rapid and convenient process. The method worked well with alkyl, aryl, and heterocyclic aldehydes and for a variety of substituents in the benzenic part of the molecule. Similar reactions employing ketones instead of aldehydes were less efficient. Although some dihydroquinazolines did form, they were accompanied by several byproducts. Surprisingly, in each case, one of the byproducts was a quinoline derivative, and a plausible mechanism to account for this rearrangement is proposed.
