703-63-9

Basic information

• Product Name: 2,4-Dimethylquinazoline
• Synonyms: 2,4-Dimethylquinazoline;DiMethylquinazoline
• CAS NO: 703-63-9
• Molecular Formula: C₁₀H₁₀N₂
• Molecular Weight: 158.2
• Mol File: 703-63-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 70 °C
• Boiling Point: 203.3 °C at 760 mmHg
• Flash Point: 61.9 °C
• Appearance: /
• Density: 1.109 g/cm³
• Vapor Pressure: 0.399mmHg at 25°C
• Refractive Index: 1.617
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.46±0.50(Predicted)
• CAS DataBase Reference: 2,4-Dimethylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethylquinazoline(703-63-9)
• EPA Substance Registry System: 2,4-Dimethylquinazoline(703-63-9)

Safety Data

• Hazardous Substances Data: 703-63-9(Hazardous Substances Data)

Usage

General Description

2,4-Dimethylquinazoline is a chemical compound that belongs to the class of organic compounds known as quinazolines, which are polycyclic aromatic compounds containing a quinazoline moiety, a structure formed from the fusion of two benzene and one pyrimidine ring. It is characterized by the presence of two methyl groups at the 2nd and 4th positions of the quinazoline ring. 2,4-Dimethylquinazoline is known for its low solubility in water, and it is primarily used in various applications in chemical research due to its specific structural properties. Even though it is not naturally produced, it can be synthesized in laboratories using specific chemical reactions. It is important to handle this compound with care as there are no detailed studies about its potential health effects.

InChI:InChI=1/C10H10N2/c1-7-9-5-3-4-6-10(9)12-8(2)11-7/h3-6H,1-2H3

Upstream product

• 1044742-98-4 1-(2-aminophenyl)ethanone O-phenyl oxime 
• 67-64-1 acetone 

Downstream Products

• 24688-36-6 2-methyl-6-nitroquinazolin-4(3H)-one 
• 1620483-90-0 (E,E)-2,4-bis(4-diphenylaminostyryl)quinazoline 
• 1620483-78-4 (E,E)-2,4-bis(4-dimethylaminostyryl)quinazoline 
• 1591672-09-1 5-methyl-3-phenylimidazo[1,5-c]quinazoline 
• 1452815-38-1 (2-methylquinazolin-4-yl)(p-tolyl)methanone 
• 1452815-37-0 (2-methylquinazolin-4-yl)(m-tolyl)methanone 
• 1452815-36-9 (2-methylquinazolin-4-yl)(o-tolyl)methanone 
• 101290-94-2 (2-methylquinazolin-4-yl)(phenyl)methanone 
• 140640-35-3 (4-methoxyphenyl)(2-methylquinazolin-4-yl)methanone 
• 1452815-35-8 (2-methylquinazolin-4-yl)(4-nitrophenyl)methanone 
• 1452815-42-7 methyl 4-(2-methylquinazoline-4-carbonyl)benzoate 
• 1452815-41-6 4-(2-methylquinazoline-4-carbonyl)benzaldehyde 
• 1452815-40-5 4-(2-methylquinazoline-4-carbonyl)benzonitrile 
• 1452815-39-2 (4-fluorophenyl)(2-methylquinazolin-4-yl)methanone 

Relevant articles and documents

Microwave-promoted syntheses of quinazolines and dihydroquinazolines from 2-aminoarylalkanone O-phenyl oximes

(Chemical Equation Presented) A wide range of biologically active compounds contain the quinazoline ring system. A new free-radical-based method of making functionalized quinazolines is described, which relies on microwave-promoted reactions of O-phenyl oximes with aldehydes. A small set of 2-aminoaryl alkanone O-phenyl oximes was prepared and shown to produce dihydroquinazolines when mixed with an aldehyde in toluene and subjected to microwave heating. When ZnCl2 was included in the reaction mixture, fully aromatic quinazolines were produced in high yields by a rapid and convenient process. The method worked well with alkyl, aryl, and heterocyclic aldehydes and for a variety of substituents in the benzenic part of the molecule. Similar reactions employing ketones instead of aldehydes were less efficient. Although some dihydroquinazolines did form, they were accompanied by several byproducts. Surprisingly, in each case, one of the byproducts was a quinoline derivative, and a plausible mechanism to account for this rearrangement is proposed.