7031-25-6

Upstream product

• 106-54-7 p-Chlorothiophenol 
• 18803-44-6 sodium p-chlorothiophenolate 
• 3405-88-7 (4-chlorophenylthio)acetic acid 

Downstream Products

• 67141-48-4 N,N-Di-sec-butyl-2-(4-chloro-phenylsulfanyl)-acetamide 
• 32297-67-9 Aethyl-N-(4-chlorphenyl-mercaptoacetyl)-3-chlor-2,6-dimethoxybenzohydroxamat 
• 30161-03-6 1-Butylsulfanyl-4-chloro-2-phenylethynyl-benzene 
• 28540-36-5 5-chloro-3-phenylbenzo[b]thiophene 
• 849403-88-9 5-chloro-2-fluoro-3-phenylbenzothiophene 
• 93535-08-1 <4-Chlor-phenylmercapto>-essigsaeure-anilid 
• 30893-78-8 (4-Chloro-phenylsulfanyl)-ethaneperoxoic acid tert-butyl ester 
• 35859-44-0 2-Diethylaminoethyl p-chlorophenylthioacetate hydrochloride 
• 120680-88-8 2-[2-(4-Chloro-phenylsulfanyl)-acetylamino]-3-phenyl-propionic acid 

Relevant academic research and scientific papers

Aromatic ring-opening of 2-fluorobenzothiophenes by alkyllithiums

Diphenylacetylenes are obtained when alkyllithium reagents are added to 3-aryl-2-fluorobenzothiophenes at low temperature. The aromatic ring-opening mechanism involves a nucleophilic addition of the alkyllithium to the sulfur atom of the thiophene. The re

2-(4-R-Phenoxy/phenylthio)alkanoic esters of l-lupinine

Considering the great pharmacological interest in phenoxy/phenylthioalkanoic esters of open-chain or cyclic aminoalcohols, a set of ten such esters of lupinine was prepared. Initially, their ability to displace [3H]QNB from rat brain preparation was investigated. With the exception of two, all the prepared esters exhibited good affinity to muscarinic receptors (on a non-selective basis), with pKi in the range 6.67-7.68.